Extrahepatic Complications of Nonalcoholic Fatty Liver Disease

被引:43
|
作者
Chacko, Kristina R. [1 ]
Reinus, John [1 ]
机构
[1] Albert Einstein Coll Med, Dept Med, 111 East 210th St,Rosenthal 2C, Bronx, NY 10467 USA
关键词
Nonalcoholic fatty liver disease (NAFLD); Extrahepatic complications; Metabolic syndrome; Cardiovascular disease; OBSTRUCTIVE SLEEP-APNEA; CHRONIC KIDNEY-DISEASE; LYSOSOMAL ACID LIPASE; POLYCYSTIC-OVARY-SYNDROME; ESTER STORAGE DISEASE; CARDIOVASCULAR-DISEASE; INSULIN-RESISTANCE; INCREASED RISK; METABOLIC SYNDROME; HEPATIC STEATOSIS;
D O I
10.1016/j.cld.2015.10.004
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver disease that is often associated with the metabolic syndrome. There is a growing awareness that extrahepatic complications occur in individuals with NAFLD, especially an increased risk of cardiovascular disease. Development of diabetes mellitus, chronic kidney disease, colorectal cancer, and endocrinopathies has been linked to NAFLD. This article reviews the extrahepatic complications affecting individuals with NAFLD and the pathogenesis underlying their development.
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页码:387 / +
页数:16
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