Evaluation of rapid antigen detection kits for detection of SARS-CoV-2 B.1.617.2 virus

被引：3
|
作者：
Mak, Gannon C. K. [1 ]
Lau, Stephen S. Y. [1 ]
Wong, Kitty K. Y. [1 ]
Chow, Nancy L. S. [1 ]
Lau, Chi-Shan [1 ]
Lam, Edman T. K. [1 ]
Ng, Ken H. L. [1 ]
Chan, Rickjason C. W. [1 ]
机构：
[1] Ctr Hlth Protect, Dept Hlth, Publ Hlth Lab, Microbiol Div,Serv Branch, Hong Kong, Peoples R China
来源：
FUTURE VIROLOGY | 2022年 / 17卷 / 06期
关键词：
SARS-CoV-2; COVID-19; B; 1; 617; 2; delta; rapid antigen detection; ANALYTICAL SENSITIVITY; TESTS;
D O I：
10.2217/fvl-2021-0229
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Aim: Currently, there is lack of data regarding rapid antigen detection (RAD) kits to detect SARS-CoV-2 B.1.617.2 virus. Objective: The purpose of this evaluation is to assess analytical sensitivity of 12 RAD kits against SARS-CoV-2 B.1.617.2. Study design: Analytical sensitivity was determined by limit of detection (LOD). A serial tenfold dilution set from a respiratory specimen collected from a COVID-19 patient infected by SARS-CoV-2 B.1.617.2 was used. RT-PCR was used as a reference method. Results: The LOD results showed that 11 and one RAD kits were 100- and 1000-fold less sensitive than RT-PCR respectively. Conclusion: The results showed that the RAD kits evaluated in this study may be used for first-line screening of the SARS-CoV-2 B.1.617.2 variant.
引用
收藏
页码：387 / 392
页数：6
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