We present a 12802 four-quadrant programmable current-mode analog vector-matrix multiplier (VMM). The proposed multiplier cell operates on a 3.3V supply, consumes 531nW/MHz and is linear over two decades of current range. Programmability and non-volatile weight storage is obtained by using floating-gate transistors. Experimental results for a full image Discrete Cosine Transform (DCT) using the proposed architecture is presented. The IC prototype was fabricated in a 0.5mum CMOS process and occupies 0.83mm(2) of area.