Antibody-Drug Conjugates for Immunology

被引：9
|
作者：
Dragovich, Peter S. [1 ]
机构：
[1] Genentech Inc, San Francisco, CA 94080 USA
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2022年 / 65卷 / 06期
关键词：
D O I：
10.1021/acs.jmedchem.2c00339
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The application of antibody-drug conjugates (ADCs) to fields outside of oncology is increasing but is still relatively uncommon. A recent publication describes the conjugation of glucocorticoid receptor modulators to antibodies as a means of improving the separation between desired anti-inflammatory activity and unwanted systemic side effects
引用
收藏
页码：4496 / 4499
页数：4
相关论文
共 50 条
  • [1] Antibody-Drug Conjugates
    Kumar, Amit
    White, Jason
    Christie, R. James
    Dimasi, Nazzareno
    Gao, Changshou
    [J]. ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 50: PLATFORM TECHNOLOGIES IN DRUG DISCOVERY AND VALIDATION, 2017, 50 : 441 - 480
  • [2] Antibody-Drug Conjugates
    Cao Gang
    Huang Zuogang
    Cheng Jiefei
    Jiang Biao
    [J]. PROGRESS IN CHEMISTRY, 2014, 26 (2-3) : 467 - 477
  • [3] Antibody-Drug Conjugates
    Ashutosh A. Kulkarni
    Hovhannes J. Gukasyan
    [J]. Pharmaceutical Research, 2015, 32 : 3451 - 3452
  • [4] Antibody-Drug Conjugates
    Peng, Li
    Chen, Xiaoyuan
    [J]. BIOCONJUGATE CHEMISTRY, 2015, 26 (11) : 2169 - 2169
  • [5] Antibody-drug conjugates
    Zolot, Rachel S.
    Basu, Satarupa
    Million, Ryan P.
    [J]. NATURE REVIEWS DRUG DISCOVERY, 2013, 12 (04) : 259 - 260
  • [6] Antibody-drug conjugates
    Ornes, Stephen
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (34) : 13695 - 13695
  • [7] ANTIBODY-DRUG CONJUGATES
    EMBLETON, MJ
    [J]. BRITISH JOURNAL OF CANCER, 1985, 52 (04) : 653 - 653
  • [8] Antibody-Drug Conjugates
    Kulkarni, Ashutosh A.
    Gukasyan, Hovhannes J.
    [J]. PHARMACEUTICAL RESEARCH, 2015, 32 (11) : 3451 - 3452
  • [9] BUILDING ANTIBODY-DRUG CONJUGATES
    Thayer, Ann M.
    [J]. CHEMICAL & ENGINEERING NEWS, 2014, 92 (03) : 13 - +
  • [10] Monoclonal antibody-drug conjugates
    Hamann, PR
    [J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 2005, 15 (09) : 1087 - 1103
12345