Synthesis and crystal structure of spiro[1-bromo(S)-4-(R)-hydroxy-5-oxa-6-oxo-bicyclo[3.1.0]hexane-2,2′-(3′-diethyl-α-(S)-4"-Cl-benzyloxypbgsphonyl-4′-(1R,2S,5R)-menthyloxvbutyrolactone)]

被引：0

作者：

Fan, XE ^{[1
]}

Fu, YQ ^{[1
]}

Wang, JG ^{[1
]}

Chen, QH ^{[1
]}

机构：

[1] Luoyang Normal Coll, Dept Chem, Luoyang 470022, Peoples R China

来源：

CHINESE JOURNAL OF STRUCTURAL CHEMISTRY | 2005年 / 24卷 / 02期

关键词：

functionalized phosphorus-cyclopropane compound; multiple chiral centers; crystal structure;

D O I：

暂无

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The title compound, spiro[1-bromo(S)-4-(R)-hydroxy-5-oxa-6-oxo-bicyclo[3.1.0]-hxane-2,2'-(3'-dieihyl-alpha-(S)-4"-Cl-benzyloxyphosphonyl-4'-(1R,2S,5R)-menthyloxybutyrolact- one)] has been synthesized via the tandem asymmetric reaction and it crystallizes in a monoclinic system, space group P2(1) with a = 11.067(3), b = 12.484(2), c = 12.356(2) Angstrom, beta = 101.95degrees, C29H39BrClO10P, M-r = 693.93, V = 1670.2(6) Angstrom(3), Z = 2, D-c = 1.380 g/cm(3), lambda(MoKalpha) = 0.071073 nm, mu = 1.410 mm(-1), F(000) = 720, the final R = 0.0570 and wR = 0.0758 for 6190 observed reflections with I > 2sigma(I). The structure is characterized by the special combination of biologic phosphonyl group and one cyclopropane as wells as two butyrolactones. The intermolecular hydrogen bond between O(3)-H(3A)O-...(10) in the crystal lattice has been observed.

引用

页码：163 / 168

页数：6

共 50 条

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