An ABC of drug-related problems

被引：71
|
作者：
Meyboom, RHB
Lindquist, M
Egberts, ACG
机构：
[1] Uppsala Monitoring Ctr, WHO, Collaborating Ctr Int Drug Monitoring, S-75320 Uppsala, Sweden
[2] Netherlands Pharmacovigilance Fdn, LAREB, Shertogenbosch, Netherlands
[3] Univ Utrecht, Fac Pharm, Dept Pharmacoepidemiol & Phamactherapy, Utrecht, Netherlands
[4] TweeSteden Hosp, Tilburg, Netherlands
来源：
DRUG SAFETY | 2000年 / 22卷 / 06期
关键词：
D O I：
10.2165/00002018-200022060-00001
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The problems relating to the use of medicines are manifold. They may differ in pharmacological, pathological, epidemiological and legal respects, and may have different consequences, for example, as regards scientific study, regulation or rational use. Pharmacovigilance is concerned with all such problems: adverse effects and interactions as well as problems relating to ineffectiveness, inappropriate use, counterfeiting, dependence or poisoning. Practically all medicine-related problems can be classified in one basic system, taking into account their characteristics and distinctions. This system distinguishes between appropriate and inappropriate drug use, dose-related problems, and types A ('drug actions'), B ('patient reactions') and C ('statistical') adverse effects. This classification may serve as an educational tool and may be useful in when choosing a study method and for the design of effective strategies in pharmacovigilance.
引用
收藏
页码：415 / 423
页数：9
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