The ionosphere is subject to many variations, notably the seasonal and solar activity cycles and the influences of geomagnetic activity, which are well documented even though imperfectly understood. These well-known variations make it difficult to detect long-term or secular changes, whether natural and man-made. Nevertheless, the ionospheric record now extends over 65 years and it is becoming feasible to investigate possible long-term changes. Possible causes of change include variations of solar activity, the secular variation of the geomagnetic field, global cooling in the upper atmosphere which would lower the ionospheric F2-layer, and changes in minor constituents. To detect any such changes, it is essential to maintain a basic world-wide programme of upper atmospheric and geomagnetic monitoring, and to ensure that the data are readily accessible to researchers. (C) 1997 COSPAR. Published by Elsevier Science Ltd.