Developments in high-speed countercurrent chromatography and its applications in the separation of terpenoids and saponins

被引：57
|
作者：
Song, Hua [1 ]
Lin, Jianhong [1 ]
Zhu, Xuan [1 ]
Chen, Qing [1 ]
机构：
[1] Xiamen Univ, Sch Pharmaceut Sci, Dept Pharm, Xiamen, Fujian, Peoples R China
来源：
JOURNAL OF SEPARATION SCIENCE | 2016年 / 39卷 / 08期
基金：
中国国家自然科学基金;
关键词：
countercurrent chromatography; saponins; terpenoids; COIL PLANET CENTRIFUGE; LARGE-SCALE SEPARATION; SUPERCRITICAL-FLUID EXTRACTION; IONIZATION MASS-SPECTROMETRY; LIGHT-SCATTERING DETECTION; 2-PHASE SOLVENT SYSTEMS; PREPARATIVE SEPARATION; PROTEIN SEPARATION; PLATYCODI-RADIX; PANAX-GINSENG;
D O I：
10.1002/jssc.201501199
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
High-speed countercurrent chromatography is a liquid-liquid separation chromatographic technique, which has the unique feature of eliminating irreversible adsorption using liquid support medium, and is widely used in research and development of traditional Chinese medicine, biochemistry, food, environment analysis, and so on. In this review, some new developments of countercurrent chromatography, for instance cross-axis countercurrent chromatography, dual countercurrent chromatography, foam countercurrent chromatography, and pH-zone-refining countercurrent chromatography are presented. Furthermore, the research and progress in high-speed countercurrent chromatography techniques and its application in the separation and purification of terpenoids and saponins are reviewed.
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页码：1574 / 1591
页数：18
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