共 29 条
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- [2] A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase[J]. NATURE, 2016, 535 (7611) : 252 - +Matyskiela, Mary E.论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USALu, Gang论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAIto, Takumi论文数: 0 引用数: 0 h-index: 0机构: Tokyo Med Univ, Dept Nanoparticle Translat Res, Shinjuku Ku, Tokyo 1608402, Japan Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAPagarigan, Barbra论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USALu, Chin-Chun论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAMiller, Karen论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAFang, Wei论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAWang, Nai-Yu论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USANguyen, Derek论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAHouston, Jack论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USACarmel, Gilles论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USATran, Tam论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USARiley, Mariko论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USANosaka, Lyn'Al论文数: 0 引用数: 0 h-index: 0机构: Scripps Res Inst, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USALander, Gabriel C.论文数: 0 引用数: 0 h-index: 0机构: Scripps Res Inst, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAGaidarova, Svetlana论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAXu, Shuichan论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USARuchelman, Alexander L.论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAHanda, Hiroshi论文数: 0 引用数: 0 h-index: 0机构: Tokyo Med Univ, Dept Nanoparticle Translat Res, Shinjuku Ku, Tokyo 1608402, Japan Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USACarmichael, James论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USADaniel, Thomas O.论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USACathers, Brian E.论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USALopez-Girona, Antonia论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USAChamberlain, Philip P.论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA
- [3] Targeting GSPT1 by a novel cereblon E3 ligase modulator for the treatment of Acute Lymphoblastic Leukemia[J]. MOLECULAR CANCER THERAPEUTICS, 2021, 20 (12)Keramatnia, Fatemeh论文数: 0 引用数: 0 h-index: 0Chang, Yunchao论文数: 0 引用数: 0 h-index: 0Nishiguchi, Gisele论文数: 0 引用数: 0 h-index: 0Min, Jaeki论文数: 0 引用数: 0 h-index: 0Mullighan, Charles论文数: 0 引用数: 0 h-index: 0Fischer, Marcus论文数: 0 引用数: 0 h-index: 0Rankovic, Zoran论文数: 0 引用数: 0 h-index: 0Keramatnia, Fatemeh论文数: 0 引用数: 0 h-index: 0
- [4] Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library[J]. ACS CHEMICAL BIOLOGY, 2020, 15 (10) : 2722 - 2730Powell, Chelsea E.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USADu, Guangyan论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USAChe, Jianwei论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USAHe, Zhixiang论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USADonovan, Katherine A.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USAYue, Hong论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USAWang, Eric S.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA论文数: 引用数: h-index:机构:Zhang, Tinghu论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USAFischer, Eric S.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USAGray, Nathanael S.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA
- [5] CC-90009, a Novel Cereblon E3 Ligase Modulator, Targets GSPT1 for Degradation to Induce Potent Tumoricidal Activity Against Acute Myeloid Leukemia (AML)[J]. BLOOD, 2019, 134Lopez-Girona, Antonia论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USALu, Gang论文数: 0 引用数: 0 h-index: 0机构: Celgene, San Diego, CA USA Celgene Corp, San Diego, CA USARychak, Emily论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USAMendy, Derek论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USALu, Chin-Chun论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USARappley, Irit论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USAFontanillo, Celia论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USACathers, Brian E.论文数: 0 引用数: 0 h-index: 0机构: Formerly Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USADaniel, Thomas O.论文数: 0 引用数: 0 h-index: 0机构: Formerly Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USAHansen, Joshua论文数: 0 引用数: 0 h-index: 0机构: Celgene Corp, San Diego, CA USA Celgene Corp, San Diego, CA USA
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JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (11) : 7296 - 7311Nishiguchi, Gisele论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAKeramatnia, Fatemeh论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA Univ Tennessee, Dept Pharmaceut Sci, Hlth Sci Ctr, Memphis, TN 38163 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAMin, Jaeki论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAChang, Yunchao论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Pathol, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAJonchere, Barbara论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Tumor Cell Biol, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USADas, Sourav论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAActis, Marisa论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAPrice, Jeanine论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAChepyala, Divyabharathi论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAYoung, Brandon论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAMcGowan, Kevin论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USASlavish, P. Jake论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAMayasundari, Anand论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAJarusiewicz, Jamie A.论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAYang, Lei论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USALi, Yong论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAFu, Xiang论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAGarrett, Shalandus H.论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAPapizan, James B.论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Ctr Adv Genome Engn, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAKodali, Kiran论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Ctr Prote & Metabol, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAPeng, Junmin论文数: 0 引用数: 0 h-index: 0机构: St Jude Childrens Res Hosp, Ctr Prote & Metabol, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Dev Neurobiol, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Struct Biol, Memphis, TN 38105 USA St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USAMiller, Shondra M. 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