One pot light assisted green synthesis, storage and antimicrobial activity of dextran stabilized silver nanoparticles

被引:29
|
作者
Hussain, Muhammad Ajaz [1 ]
Shah, Abdullah [1 ]
Jantan, Ibrahim [2 ]
Tahir, Muhammad Nawaz [3 ]
Shah, Muhammad Raza [4 ]
Ahmed, Riaz [5 ]
Bukhari, Syed Nasir Abbas [2 ]
机构
[1] Univ Sargodha, Dept Chem, Sargodha 40100, Pakistan
[2] Univ Kebangsaan Malaysia, Fac Pharm, Drug & Herbal Res Ctr, Kuala Lumpur 50300, Malaysia
[3] Johannes Gutenberg Univ Mainz, Inst Inorgan & Analyt Chem, D-55128 Mainz, Germany
[4] Univ Karachi, Int Ctr Chem & Biol Sci, Karachi 75270, Pakistan
[5] Govt Coll Univ, CASP, Lahore 54000, Pakistan
关键词
Ag nanoparticles; Storage of nanoparticles; Diffused sun light; Antimicrobial activity; CHITOSAN;
D O I
10.1186/s12951-014-0053-5
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Background: Green synthesis of nanomaterials finds the edge over chemical methods due to its environmental compatibility. Herein, we report green synthesis of silver nanoparticles (Ag NPs) mediated with dextran. Dextran was used as a stabilizer and capping agent to synthesize Ag NPs using silver nitrate (AgNO3) under diffused sunlight conditions. Results: UV-vis spectra of as synthesized Ag nanoparticles showed characteristic surface plasmon band in the range from similar to 405-452 nm. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) studies showed spherical Ag NPs in the size regime of similar to 50-70 nm. Face centered cubic lattice of Ag NPs was confirmed by powder X-ray diffraction (PXRD). FT-IR spectroscopy confirmed that dextran not only acts as reducing agent but also functionalizes the surfaces of Ag NPs to make very stable dispersions. Moreover, on drying, the solution of dextran stabilized Ag NPs resulted in the formation of thin films which were found stable over months with no change in the plasmon band of pristine Ag NPs. The antimicrobial assay of the as synthesized Ag NPs showed remarkable activity. Conclusion: Being significantly active against microbes, the Ag NPs can be explored for antimicrobial medical devices.
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页数:6
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