Management of Angioimmunoblastic T-Cell Lymphoma (AITL) and other T Follicular Helper Cell lymphomas (TFH PTCL)

被引：5

作者：

Ma, Helen ^{[1
]}

O'Connor, Owen A. ^{[2
]}

Marchi, Enrica ^{[2
]}

机构：

[1] Univ Calif Irvine, Div Hematol Oncol, Long Beach, CA USA

[2] Univ Virginia, Div Hematol Oncol, Charlottesville, VA USA

来源：

SEMINARS IN HEMATOLOGY | 2021年 / 58卷 / 02期

关键词：

Angioimmunoblastic T-cell lymphoma (AITL)& nbsp; Nodal PTCL with T Follicular Helper Phenotype (PTCL TFH); Epigenetic Modifiers; EPSTEIN-BARR-VIRUS; PIVOTAL PHASE-II; OPEN-LABEL; B-CELLS; IMMUNOBLASTIC LYMPHADENOPATHY; MUTATIONAL LANDSCAPE; CD30; EXPRESSION; SINGLE-AGENT; PRALATREXATE; MULTICENTER;

D O I：

10.1053/j.seminhematol.2021.03.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Despite the remarkable improvements in the treatment and outcome of patients with aggressive B-cell lymphoma, the peripheral T-cell lymphomas (PTCL) continue to carry a poor prognosis with the presently available treatment options. The PTCL are very rare diseases that account for only 10,0 0 0 to 15,0 0 0 new cases per year in the United States. The World Health Organization's 2016 classification describes 29 distinct subtypes of PTCL, thus making these both rate and incredibly heterogenous. The 2 most common forms of PTCL, for example, peripheral T-cell lymphoma-not otherwise specified and angioimmunoblastic T-cell lymphoma , have an incidence of only 2500 and 1800 cases per year respectively, in the United States (c) 2021 Elsevier Inc. All rights reserved.

引用

页码：95 / 102

页数：8

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