The mystery of monozygotic twinning II: What can monozygotic twinning tell us about Amyoplasia from a review of the various mechanisms and types of monozygotic twinning?

被引：10

作者：

Hall, Judith G. ^{[1
,2
]}

机构：

[1] Univ British Columbia, Vancouver, BC, Canada

[2] British Columbia Childrens Hosp, Dept Pediat & Med Genet, Womens Hlth Ctr British Columbia, Vancouver, BC, Canada

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS PART A | 2021年 / 185卷 / 06期

关键词：

Amyoplasia; familial MZ twinning; IVF MZ twinning; overripe ova; spontaneous MZ twinning; twin– twin transfusion syndrome; ASSISTED REPRODUCTIVE TECHNOLOGY; IN-VITRO FERTILIZATION; GENOME-WIDE ANALYSIS; MONOCHORIONIC TWINS; STEM-CELLS; VASCULAR ANASTOMOSES; CONGENITAL-ANOMALIES; 9-BANDED ARMADILLO; HUMAN PLACENTATION; SPECIAL ATTENTION;

D O I：

10.1002/ajmg.a.62177

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Monozygotic (MZ) twins ("identical twins") are essentially unique to human beings. Why and how they arise is not known. This article reviews the possible different types of MZ twinning recognized in the previous article on twins and arthrogryposis. There appear to be at least three subgroups of MZ twinning: spontaneous, familial, and those related to artificial reproductive technologies. Each is likely to have different etiologies and different secondary findings. Spontaneous MZ twinning may relate to "overripe ova." Amyoplasia, a specific nongenetic form of arthrogryposis, appears to occur in spontaneous MZ twinning and may be related to twin-twin transfusion.

引用

页码：1822 / 1835

页数：14

共 35 条

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