Higher rates of all-cause mortality and resource utilization during episodes-of-care for diabetic foot ulceration

被引:13
|
作者
Petersen, Brian J. [1 ]
Linde-Zwirble, Walter T. [2 ]
Tan, Tze-Woei [3 ]
Rothenberg, Gary M. [4 ]
Salgado, Simon J. [1 ]
Bloom, Jonathan D. [1 ]
Armstrong, David G. [5 ]
机构
[1] Podimetr Inc, 100 Dover St, Somerville, MA 02144 USA
[2] Trexin Consulting Inc, 601 Carlson Pkwy, Minneapolis, MN 55305 USA
[3] Univ Arizona, Coll Med, Dept Surg, Tucson, AZ 85724 USA
[4] Univ Michigan, Dept Internal Med, Med Sch, Ann Arbor, MI 48109 USA
[5] Univ Southern Calif, Dept Surg, Keck Sch Med, Los Angeles, CA USA
关键词
Diabetic foot ulcers; Episodes of care; Amputations; Resource utilization; Hospitalizations; Prevention; ULCERS;
D O I
10.1016/j.diabres.2021.109182
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims: Our primary objective was to determine whether all-cause rates of mortality and resource utilization were higher during periods of diabetic foot ulceration. In support of this objective, a secondary objective was to develop and validate an episode-of-care model for diabetic foot ulceration.Methods: We evaluated data from the Medicare Limited Data Set between 2013 and 2019. We defined episodes-of-care by clustering diabetic foot ulcer related claims such that the longest time interval between consecutive claims in any cluster did not exceed a duration which was adjusted to match two aspects of foot ulcer episodes that are well-established in the literature: healing rate at 12 weeks, and reulceration rate following healing. We compared rates of outcomes during periods of ulceration to rates immediately following healing to estimate incidence ratios.Results: The episode-of-care model had a minimum mean relative error of 4.2% in the two validation criteria using a clustering duration of seven weeks. Compared to periods after healing, all-cause inpatient admissions were 2.8 times more likely during foot ulcer episodes and death was 1.5 times more likely.Conclusions: A newly-validated episode-of-care model for diabetic foot ulcers suggests an underappreciated association between foot ulcer episodes and all-cause resource utilization and mortality.(c) 2021 Published by Elsevier B.V.
引用
收藏
页数:9
相关论文
共 50 条
  • [1] Influence of Foot Ulceration on All-Cause and Cardiovascular Mortality in Diabetic Patients A Case-Control Study
    Qiu, Liangzhi
    Li, Yongjie
    Yang, Chuan
    Mao, Xiaoqun
    Mai, Lifang
    Zhu, Lisi
    Xie, Wen
    [J]. JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING, 2022, 49 (02) : 175 - 179
  • [2] All-cause and cardiovascular mortality in a consecutive series of patients with diabetic foot osteomyelitis
    Ricci, Lucia
    Scatena, Alessia
    Tacconi, Danilo
    Ventoruzzo, Giorgio
    Liistro, Francesco
    Bolognese, Leonardo
    Monami, Matteo
    Mannucci, Edoardo
    [J]. DIABETES RESEARCH AND CLINICAL PRACTICE, 2017, 131 : 12 - 17
  • [3] The association of ulceration of the foot with cardiovascular and all-cause mortality in patients with diabetes: a meta-analysis
    J. R. W. Brownrigg
    J. Davey
    P. J. Holt
    W. A. Davis
    M. M. Thompson
    K. K. Ray
    R. J. Hinchliffe
    [J]. Diabetologia, 2012, 55 : 2906 - 2912
  • [4] The association of ulceration of the foot with cardiovascular and all-cause mortality in patients with diabetes: a meta-analysis
    Brownrigg, J. R. W.
    Davey, J.
    Holt, P. J.
    Davis, W. A.
    Thompson, M. M.
    Ray, K. K.
    Hinchliffe, R. J.
    [J]. DIABETOLOGIA, 2012, 55 (11) : 2906 - 2912
  • [5] All-Cause Health Care Resource Utilization in Individuals with Sickle Cell Disease
    Rajpura, Jigar
    Thomas, Joseph, III
    [J]. BLOOD, 2015, 126 (23)
  • [6] Time in range in relation to amputation and all-cause mortality in hospitalised patients with diabetic foot ulcers
    Xie, Puguang
    Deng, Bo
    Zhang, Xi
    Li, Yuyao
    Du, Chenzhen
    Rui, Shunli
    Deng, Wu
    Boey, Johnson
    Armstrong, David G.
    Ma, Yu
    Deng, Wuquan
    [J]. DIABETES-METABOLISM RESEARCH AND REVIEWS, 2022, 38 (02)
  • [7] All-cause mortality among diabetic foot patients and related risk factors in Saudi Arabia
    Al-Rubeaan, Khalid
    Almashouq, Mohammad K.
    Youssef, Amira M.
    Al-Qumaidi, Hamid
    Al Derwish, Mohammad
    Ouizi, Samir
    Al-Shehri, Khalid
    Masoodi, Saba N.
    [J]. PLOS ONE, 2017, 12 (11):
  • [8] Sarcopenia is an independent risk factor for all-cause mortality rate in patients with diabetic foot ulcers
    Yang, Qin
    Ni, Xia
    Zhang, Yingxiao
    Zhu, Baozhen
    Zeng, Qinglian
    Yang, Chan
    Shi, Jiale
    Zhang, Chunlin
    Cai, Jiahui
    Hu, Jinbo
    Li, Qifu
    Jiang, Yingsong
    Cheng, Qingfeng
    Cheng, Chao
    [J]. FRONTIERS IN NUTRITION, 2023, 10
  • [9] Associations of Estimated Glomerular Filtration Rate with All-Cause Mortality and Cardiovascular Mortality in Patients with Diabetic Foot Osteomyelitis
    Huang, Jianhao
    Li, Weiwei
    Wei, Suosu
    Zhou, Xing
    Nong, Yuechou
    Sun, Jingxia
    Zhai, Zhenwei
    Lu, Wensheng
    [J]. INTERNATIONAL JOURNAL OF GENERAL MEDICINE, 2021, 14 : 4499 - 4509
  • [10] Seizure Frequency, Overall Healthcare Resource Utilization, and all-Cause Mortality in Children with Epilepsy in the UK
    Chin, R.
    Myland, M.
    Tsong, W.
    Power, G. S.
    Varga, S.
    Li, H.
    Nordli, D.
    [J]. EPILEPSIA, 2018, 59 : S13 - S13