Antiretroviral Therapy for Control of the HIV-associated Tuberculosis Epidemic in Resource-Limited Settings

被引：91
|
作者：
Lawn, Stephen D. [1 ,2 ]
Kranzer, Katharina [1 ,2 ]
Wood, Robin [1 ]
机构：
[1] Univ Cape Town, Desmond Tutu HIV Ctr, Inst Infect Dis & Mol Med, Fac Hlth Sci, ZA-7925 Cape Town, South Africa
[2] London Sch Hyg & Trop Med, Dept Infect & Trop Dis, Clin Res Unit, London WC1, England
来源：
CLINICS IN CHEST MEDICINE | 2009年 / 30卷 / 04期
基金：
美国国家卫生研究院; 英国惠康基金;
关键词：
HIV; Tuberculosis; Antiretroviral; Disease control; Mortality; ISONIAZID PREVENTIVE THERAPY; RECONSTITUTION INFLAMMATORY SYNDROME; RIO-DE-JANEIRO; INFECTED PATIENTS; SOUTH-AFRICA; IMMUNE RECONSTITUTION; RISK-FACTORS; RECURRENT TUBERCULOSIS; MYCOBACTERIUM-TUBERCULOSIS; ACTIVE TUBERCULOSIS;
D O I：
10.1016/j.ccm.2009.08.010
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Great progress has been made over the past few years in HIV testing in patients who have tuberculosis (TB) and in the scale-up of antiretroviral therapy. More than 3 million people in resource-limited settings were estimated to have started antiretroviral therapy by the end of 2007 and 2 million of these were in sub-Saharan Africa. However, little is known about what impact this massive public health intervention will have on the HIV-associated TB epidemic or how antiretroviral therapy might be used to best effect TB control. This article provides an in-depth review of these issues.
引用
收藏
页码：685 / +
页数：16
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