Stochastic local search algorithms for DNA word design

被引:0
|
作者
Tulpan, DC [1 ]
Hoos, HH [1 ]
Condon, AE [1 ]
机构
[1] Univ British Columbia, Dept Comp Sci, Vancouver, BC V6T 1Z4, Canada
来源
DNA COMPUTING | 2003年 / 2568卷
关键词
DNA word design; combinatorics; stochastic local search; coding theory; hamming distance; GC content;
D O I
暂无
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
We present results on the performance of a stochastic local search algorithm for the design of DNA codes, namely sets of equal-length words over the nucleotides alphabet {A, C, G, T} that satisfy certain combinatorial constraints. Using empirical analysis of the algorithm, we gain insight on good design principles. We report several cases in which our algorithm finds word sets that match or exceed the best previously known constructions.(1)
引用
收藏
页码:229 / 241
页数:13
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