Inhibition of the PI3K pathway in HER2-positive gastric cancer

被引：0
|
作者：
Toomey, S. [1 ]
Mezynski, M. J. [1 ]
Farrelly, A. [1 ]
Armstrong, P. [1 ]
McAuley, J. [1 ]
Holohan, C. [2 ]
Elamin, Y. Y. [1 ]
Rafee, S. [2 ]
Workman, J. [1 ]
Cremona, M. [1 ]
Grogan, L. [3 ]
Breathnach, O. S. [3 ]
Morris, P. G. [3 ]
Fay, J. [4 ]
Kay, E. [4 ]
Hennessy, B. T. [3 ]
机构：
[1] RCSI Mol Med Labs, Dept Mol Med, Dublin, Ireland
[2] St James Hosp, Med Oncol, Dublin, Ireland
[3] Beaumont Hosp, Ctr Canc, Med Oncol, Dublin, Ireland
[4] Royal Coll Surgeons Ireland, Histopathol, Dublin, Ireland
来源：
ANNALS OF ONCOLOGY | 2019年 / 30卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
807P
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Targeting the PI3K pathway in HER2-positive gastric cancer
    Toomey, S.
    Farrelly, A. M.
    Mezynski, M. J.
    Carr, A.
    Armstrong, P.
    Mcauley, J.
    Fay, J.
    Kay, E. W.
    Cremona, M.
    Holohan, C.
    Keegan, N. M.
    Elamin, Y.
    Rafee, S.
    Hennessy, B. T.
    [J]. EUROPEAN JOURNAL OF CANCER, 2018, 103 : E142 - E142
  • [2] Genomic Profiling of HER2-Positive Gastric Cancer: PI3K/Akt/mTOR Pathway as Predictor of Outcomes in HER2-Positive Advanced Gastric Cancer Treated with Trastuzumab
    Diaz-Serrano, Asuncion
    Angulo, Barbara
    Dominguez, Carolina
    Pazo-Cid, Roberto
    Salud, Antonieta
    Jimenez-Fonseca, Paula
    Leon, Ana
    Carmen Galan, Maria
    Alsina, Maria
    Rivera, Fernando
    Plaza, J. Carlos
    Paz-Ares, Luis
    Lopez-Rios, Fernando
    Gomez-Martin, Carlos
    [J]. ONCOLOGIST, 2018, 23 (09): : 1092 - 1102
  • [3] HER2/PI3K/AKT pathway in HER2-positive breast cancer: A review
    Pan, Linghui
    Li, Jinling
    Xu, Qi
    Gao, Zili
    Yang, Mao
    Wu, Xiaoping
    Li, Xuesen
    [J]. MEDICINE, 2024, 103 (24)
  • [4] PI3K inhibitors in trastuzumab-resistant HER2-positive breast cancer cells with PI3K pathway alterations
    Chung, Wei-Pang
    Huang, Wei-Lun
    Lee, Chun-Hui
    Hsu, Hui-Ping
    Huang, Wan-Ling
    Liu, You-Yu
    Su, Wu-Chou
    [J]. AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 12 (07): : 3067 - +
  • [5] Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer
    Mezynski, M. Janusz
    Farrelly, Angela M.
    Cremona, Mattia
    Carr, Aoife
    Morgan, Clare
    Workman, Julie
    Armstrong, Paul
    McAuley, Jennifer
    Madden, Stephen
    Fay, Joanna
    Sheehan, Katherine M.
    Kay, Elaine W.
    Holohan, Ciara
    Elamin, Yasir
    Rafee, Shereen
    Morris, Patrick G.
    Breathnach, Oscar
    Grogan, Liam
    Hennessy, Bryan T.
    Toomey, Sinead
    [J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2021, 19 (01)
  • [6] Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer
    M. Janusz Mezynski
    Angela M. Farrelly
    Mattia Cremona
    Aoife Carr
    Clare Morgan
    Julie Workman
    Paul Armstrong
    Jennifer McAuley
    Stephen Madden
    Joanna Fay
    Katherine M. Sheehan
    Elaine W. Kay
    Ciara Holohan
    Yasir Elamin
    Shereen Rafee
    Patrick G. Morris
    Oscar Breathnach
    Liam Grogan
    Bryan T. Hennessy
    Sinead Toomey
    [J]. Journal of Translational Medicine, 19
  • [7] Inhibition of PI3K pathway improves anti HER2 treatment efficacy in a panel of HER2 positive gastric cancer cell lines
    Gambardella, V.
    Llorca-Cardenosa, M. J.
    Castillo, J.
    Tarazona Llavero, N.
    Huerta, M.
    Rosello Keranen, S.
    Ibarolla-Villava, M.
    Ribas, G.
    Gil, A.
    Cervantes, A.
    [J]. ANNALS OF ONCOLOGY, 2016, 27
  • [8] Components of the PI3K/Akt pathway as prognostic factors in metastatic HER2-positive breast cancer treated with trastuzumab
    Veenstra, C.
    Ellegard, S.
    Perez-Tenorio, G.
    Fagerstrom, V.
    Garsjo, J.
    Briedis, K.
    Sundqvist, M.
    Malmstrom, A.
    Wingren, S.
    Stal, O.
    [J]. ANNALS OF ONCOLOGY, 2016, 27
  • [9] HER-2-induced PI3K signaling pathway was involved in the pathogenesis of gastric cancer
    Y F Fu
    R Gui
    J Liu
    [J]. Cancer Gene Therapy, 2015, 22 : 145 - 153
  • [10] HER-2-induced PI3K signaling pathway was involved in the pathogenesis of gastric cancer
    Fu, Y. F.
    Gui, R.
    Liu, J.
    [J]. CANCER GENE THERAPY, 2015, 22 (03) : 145 - 153
12345