Effects of polysaccharides isolated from mushrooms (Lentinus edodes Berk or Agaricus blazei Murill) on the gelation of Pluronic® F127

被引：12

作者：

Menezes, Thiago Magalhaes Farias ^{[1
]}

Campelo, Matheus da Silva ^{[1
,2
]}

Lima, Ana Beatriz Nogueira ^{[1
]}

Neto, Joao Francisco Camara ^{[1
]}

Saraiva, Matheus Morais ^{[1
]}

Sousa, Joao Antonio Costa de ^{[2
]}

Gonzaga, Maria Leonia da Costa ^{[1
]}

Leal, Luzia Kalyne Almeida Moreira ^{[2
]}

Ribeiro, Maria Elenir Nobre Pinho ^{[1
]}

Ricardo, Nagila Maria Pontes Silva ^{[1
]}

Soares, Sandra de Aguiar ^{[1
]}

机构：

[1] Univ Fed Ceara, Dept Organ & Inorgan Chem, Lab Polymers & Mat Innovat, Campus Pici, BR-60440900 Fortaleza, CE, Brazil

[2] Univ Fed Ceara, Ctr Pharmaceut & Cosmet Studies, Dept Pharm, BR-60430370 Fortaleza, CE, Brazil

来源：

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2022年 / 642卷

关键词：

Polysaccharide; Agaricus brasiliensis; Lentinus edodes; Pluronic F127; Copolymer; EDIBLE MUSHROOMS; PURIFICATION; INHIBITION;

D O I：

10.1016/j.colsurfa.2022.128684

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

This study evaluated the effects of polysaccharides isolated from Lentinus edodes Berk and Agaricus blazei Murill mushrooms on the gelation process of the Pluronic (R) F127 (F127) copolymer. The structural characterization of these biopolymers suggested the isolation of an beta-glucan L. edodes Berk (LEB) and a proteoglycan complex A. blazei Murill (ABM). Both polysaccharides showed good rheological properties for developing pharmaceutical formulations with antioxidant activity and low cytotoxicity in human neutrophils. The characterization of the gels formed from the mixture of polysaccharides with aqueous solutions of F127 showed that the presence of these biopolymers reduces the temperature range in which F127 remains in the gel phase (G' > G "). Further-more, the thermoresponsive behavior of F127 was not lost, which favors the development of hydrogels with potential for topical use.

引用

页数：11

共 7 条

[1] Suppression of cytochrome P4501 a subfamily in mouse liver by oral intake of polysaccharides from mushrooms, Lentinus edodes and Agaricus blazei
Ashida, H
Hashimoto, T
Nonaka, Y
Fukuda, I
Kanazawa, K
Danno, G
Minato, K
Kawakami, S
Mizuno, M
FOOD FACTORS IN HEALTH PROMOTION AND DISEASE PREVENTION, 2003, 851 : 235 - 248
[2] Suppressive effect of polysaccharides from the edible and medicinal mushrooms, Lentinus edodes and Agaricus blazei, on the expression of cytochrome P450s in mice
Hashimoto, T
Nonaka, Y
Minato, K
Kawakami, S
Mizuno, M
Fukuda, I
Kanazawa, K
Ashida, H
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2002, 66 (07) : 1610 - 1614
[3] Effects of Polypropylene Glycol 400 (PPG400) on the Micellization and Gelation of Pluronic F127
de Lima, Carolina Moura
Siqueira, Sonia M. C.
de Amorim, Antonia F. V.
Costa, Kamilla B. S.
de Brito, Debora H. A.
Ribeiro, Maria E. N. P.
Ricardo, Nadja M. P. S.
Chaibunditc, Chiraphon
Yeates, Stephen G.
Ricardo, Nagila M. P. S.
MACROMOLECULES, 2015, 48 (21) : 7978 - 7982
[4] The Protective Effects of Polysaccharides from Agaricus blazei Murill Against Cadmium-Induced Oxidant Stress and Inflammatory Damage in Chicken Livers
Hu, Xuequan
Zhang, Ruili
Xie, Yingying
Wang, Hongmei
Ge, Ming
BIOLOGICAL TRACE ELEMENT RESEARCH, 2017, 178 (01) : 117 - 126
[5] The Protective Effects of Polysaccharides from Agaricus blazei Murill Against Cadmium-Induced Oxidant Stress and Inflammatory Damage in Chicken Livers
Xuequan Hu
Ruili Zhang
Yingying Xie
Hongmei Wang
Ming Ge
Biological Trace Element Research, 2017, 178 : 117 - 126
[6] INHIBITORY-ACTION OF A (1-]6)-BETA-D-GLUCAN-PROTEIN COMPLEX (F-III-2-B) ISOLATED FROM AGARICUS-BLAZEI MURILL (HIMEMATSUTAKE) ON METH-A FIBROSARCOMA-BEARING MICE AND ITS ANTITUMOR MECHANISM
ITOH, H
ITO, H
AMANO, H
NODA, H
JAPANESE JOURNAL OF PHARMACOLOGY, 1994, 66 (02): : 265 - 271
[7] Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice:: Increased small intestinal crypt survival and prolongation of average, time to animal death
Kubo, N
Myojin, Y
Shimamoto, F
Kashimoto, N
Kyo, E
Kamiya, K
Watanabe, H
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2005, 15 (03) : 401 - 406

← 1 →