Redox and pH double stimulus-responsive mesoporous silica nanoparticles for drug delivery

被引:6
|
作者
Chen, Yang [1 ]
Wang, Yi-Fan [1 ]
He, Liang [1 ]
Wang, Zhe [1 ]
Shen, You-Qing [1 ]
Cong, Hai-Lin [1 ,2 ]
Yu, Bing [1 ,2 ]
机构
[1] Qingdao Univ, Coll Chem & Chem Engn, Coll Mat Sci & Engn, Inst Biomed Mat & Engn, Qingdao, Shandong, Peoples R China
[2] Qingdao Univ, State Key Lab Biofibers & Ecotext, Qingdao, Shandong, Peoples R China
基金
中国国家自然科学基金;
关键词
Mesoporous silica nanoparticles; carbon dots; drug delivery; CHITOSAN NANOPARTICLES; CANCER-THERAPY; CARBON DOTS; NANOCARRIERS; DOXORUBICIN; DESIGN;
D O I
10.1080/00150193.2019.1592538
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Redox and pH double stimulus-responsive drug delivery platform based on chitosan (CS), carbon dots (CDs) and hyaluronic acid (HA) gated mesoporous silica nanoparticles (MSN) for drug delivery. The DDS showed excellent drug loading and release properties with good biocompatibility. In addition, the DDS exhibited fluorescence bioimaging properties. The prepared MSN-CS-CDs@HA is demonstrated to be a promising cancer treatment platform.
引用
收藏
页码:1 / 11
页数:11
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