Copper-Catalyzed Hydroamination of Terminal Allenes

被引：53

作者：

Blieck, Remi ^{[1
]}

Bahri, Janet ^{[1
]}

Taillefer, Marc ^{[1
]}

Monnier, Florian ^{[1
]}

机构：

[1] Ecole Natl Super Chim Montpellier, Inst Charles Gerhardt Montpellier, UMR 5253, CNRS,AM2N, 8 Rue Ecole Normale, F-34296 Montpellier 5, France

来源：

ORGANIC LETTERS | 2016年 / 18卷 / 06期

关键词：

INTERMOLECULAR HYDROAMINATION; INTRAMOLECULAR HYDROAMINATION; REGIOSELECTIVE ACCESS; ALLYLIC AMINES; ARYLATION; ALKENES; ALKYNES; COMPLEXES; ZIRCONIUM; EFFICIENT;

D O I：

10.1021/acs.orglett.6b00452

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ligand-free copper-catalyzed hydroamination of allenes has been accomplished in the presence of cyclic secondary amines or anilines derivatives. This novel methodology undergoes the selective generation of (E)-allylamines under smooth conditions with total regio- and stereoselectivity.

引用

页码：1482 / 1485

页数：4

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