SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL SCREENING OF DIORGANOTIN(IV) COMPLEXES DERIVED FROM 2-[(4-DIMETHYLAMINO-BENZYLIDENE)AMINO]PHENOL

被引：9
|
作者：
Rehman, Wajid [1 ]
Haq, Sirajul [1 ]
Rahim, Fazal [1 ]
Khan, Salimullah [2 ]
Waseem, Muhammad [3 ]
Nawaz, Mohsan [1 ]
Abid, Obaid-Ur-Rahman [1 ]
Qursehi, Muhammad Tauseef [4 ]
Guo, Cun-Yue [5 ]
机构：
[1] Hazara Univ, Dept Chem, Mansehra, Pakistan
[2] Abdul Khan Univ Mardan, Dept Pharm, Mardan, Pakistan
[3] COMSATS Inst Informat Technol, Dept Phys, Islamabad 44000, Pakistan
[4] Hazara Univ, Dept Phys, Mansehra, Pakistan
[5] Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2017年 / 51卷 / 02期
关键词：
2-aminophenol; 4-(dimethylamino)benzaldehyde; Schiff base; antibacterial activity; TRIORGANOTIN(IV) COMPLEXES; ORGANOTIN(IV) COMPLEXES; METAL-COMPLEXES;
D O I：
10.1007/s11094-017-1567-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Five organotin complexes have been derived from a Schiff base, 2-[(4-dimethylamino-benzylidene)amino] phenol. The synthesis of target compounds is confirmed by spectroscopic techniques: IR, H-1 NMR, and C-13 NMR. Activity of the initial Schiff base and its complexes has been tested with respect to various bacterial strains, and the results obtained are quite promising against both Gram-positive and Gram-negative bacteria.
引用
收藏
页码：115 / 118
页数：4
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