CMOS Transimpedance Amplifier for Biosensor Signal Acquisition

被引:0
|
作者
Ibrahim, Mark M. R. [1 ]
Levine, Peter M. [1 ]
机构
[1] Univ Waterloo, Dept Elect & Comp Engn, Waterloo, ON N2L 3G1, Canada
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暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We present a 1-G Omega CMOS transimpedance amplifier (TIA) suitable for processing sub-nA-level currents in electrochemical biosensor signal-acquisition circuits. Use of a two-stage active transconductor provides resistive feedback in place of a single large-area linear resistor. We engineer the TIA feedback loop to suppress output offset caused by dc input leakage currents of +/- 0.9 nA. We also implement a mechanism to tune the low-frequency cutoff of the TIA from 0.7 Hz to 500 Hz which permits operation under variable environmental conditions. We report simulated and experimental results from our custom TIA fabricated in a 3.3-V 0.35-mu m CMOS process.
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页码:25 / 28
页数:4
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