The number of overweight and obese patients undergoing renal transplantation has drastically increased in the last two decades. Studies on graft survival and complication rates of these obese patients have had conflicting results, with some reporting a significant risk and others reporting relatively good outcomes. We examined I-year outcomes in obese and nonobese patients who underwent living donor transplants at our transplant program, a slightly different approach than prior studies of deceased donor transplants into patients with high body mass index (BMI). The mean serum creatinine clearance by the modified MDRD equation at the end of 1 year in the nonobese group was 58.9 mL/min whereas the mean creatinine clearance in the obese group was 48.9 mL/min (P = .09). The length of stay, incidence of delayed graft function, and 1-year graft survival did not differ between the obese and nonobese groups. The results of this single-center experience with living donor transplant into obese subjects suggest no differences in outcomes with regard to surgical or wound complications, delayed graft function, or serum creatinine at 1 year.
机构:
Ludwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Dresden Int Univ, German Sites Dev Principles & Practice Clin Res Ha, Dresden, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Grigorescu, Melissa
Kemmner, Stephan
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Ludwig Maximilians Univ LMU, Univ Hosp Munich, Transplant Ctr, Munich, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Kemmner, Stephan
Schoenermarck, Ulf
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Ludwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Schoenermarck, Ulf
Sajin, Isidora
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Ludwig Maximilians Univ LMU, Univ Hosp Munich, Transplant Ctr, Munich, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Sajin, Isidora
Guenther, Wolfgang
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Ludwig Maximilians Univ LMU, Univ Hosp Munich, Transplant Ctr, Munich, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Guenther, Wolfgang
Cerqueira, Tiago Lemos
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Dresden Int Univ, German Sites Dev Principles & Practice Clin Res Ha, Dresden, Germany
Hosp Evangel Minas Gerais, Dept Kidney Transplant, Belo Horizonte, BrazilLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Cerqueira, Tiago Lemos
Illigens, Ben
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Dresden Int Univ, German Sites Dev Principles & Practice Clin Res Ha, Dresden, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Illigens, Ben
Siepmann, Timo
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Dresden Int Univ, German Sites Dev Principles & Practice Clin Res Ha, Dresden, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Siepmann, Timo
Meiser, Bruno
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Ludwig Maximilians Univ LMU, Univ Hosp Munich, Transplant Ctr, Munich, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Meiser, Bruno
Guba, Markus
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Ludwig Maximilians Univ LMU, Univ Hosp Munich, Transplant Ctr, Munich, Germany
Ludwig Maximilians Univ LMU, Univ Hosp Munich, Dept Gen Visceral & Transplant Surg, Munich, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Guba, Markus
Fischereder, Michael
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Ludwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Ludwig Maximilians Univ LMU, Univ Hosp Munich, Transplant Ctr, Munich, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany
Fischereder, Michael
Stang, Manfred Johannes
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Ludwig Maximilians Univ LMU, Univ Hosp Munich, Transplant Ctr, Munich, Germany
Ludwig Maximilians Univ LMU, Univ Hosp Munich, Dept Gen Visceral & Transplant Surg, Munich, GermanyLudwig Maximilians Univ LMU, Univ Hosp Munich, Dept Internal Med 4, Div Nephrol, Munich, Germany