Since 1982, the author has been successfully using Bi-Digital O-Ring Test (BDORT) electro-magnetic resonance phenomenon between 2 identical substances; i.e. between specific cancer (in vivo) of a patient and a microscope slide of identical cancer tissue to detect cancers at a very early stage. Since 2000, the author has found that when BDORT is performed while an individual with a malignant tumor is talking or singing, BDORT became (-1 approximately -10) in 94% of 200 cases and the number of openings (-) is approximately proportional to the degree of abnormality up to -10. Thus, cancer can be screened from voice by talking or singing within 1 min., without using any instrument. Also, when cancer-free persons hold slides of cancer tissue or 10 ng BDORT unit or higher Oncogene C-fos Ab2 or Integrin alpha(5)beta(1) while talking or singing over a short or long distance, BDORT always opens. To identify the type of the patient's malignancy, if BDORT is performed by an examiner holding a microscope slide of cancer tissue identical to the patient's cancer, characteristic strong BDORT resonance phenomenon appears with opening of all O-Rings formed between thumb and other fingers. When patients with myocardial infarct or various infections speak, no O-Rings open without holding identical pathological substances. Thus, it is possible to detect any type of malignancy from the voice but we cannot identify which cancer or malignancy. However, it is also possible to identify what type of cancer of what internal organ as long as a set of about 35 different tumor tissue slides is available but examining the presence of strong BDORT resonance between human voice and microscope slide of specific cancer or malignancy tissue. Based on these new findings, the author concluded that the voice of an individual with a malignancy carries information about the amount and structure of molecules present in malignant tissue.