SINGLE-MOLECULE ANALYSIS A ribosome in action

被引：7
|
作者：
Brakmann, Susanne [1 ]
机构：
[1] Tech Univ Dortmund, Dept Biol Chem, D-44227 Dortmund, Germany
来源：
NATURE | 2010年 / 464卷 / 7291期
关键词：
TRANSLATION; TIME;
D O I：
10.1038/464987a
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The manufacture of proteins by ribosomes involves complex interactions of diverse nucleic-acid and protein ligands. Single-molecule studies allow us, for the first time, to follow the synthesis of full-length proteins in real time.
引用
收藏
页码：987 / 988
页数：2
相关论文
共 50 条
  • [1] Single-molecule observations of ribosome function
    Blanchard, Scott C.
    CURRENT OPINION IN STRUCTURAL BIOLOGY, 2009, 19 (01) : 103 - 109
  • [2] Mechanistic insights into antibiotic action on the ribosome through single-molecule fluorescence imaging
    Wang, Leyi
    Wasserman, Michael R.
    Feldman, Michael B.
    Altman, Roger B.
    Blanchard, Scott C.
    ANTIMICROBIAL THERAPEUTICS REVIEWS: ANTIBIOTICS THAT TARGET THE RIBOSOME, 2011, 1241 : E1 - E16
  • [3] Single-Molecule Profiling of Ribosome Translational Phenomena
    Chen, Jin
    Petrov, Alexey
    Johansson, Magnus
    Tsai, Albert
    O'Leary, Sean E.
    Puglisi, Joseph D.
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 239A - 239A
  • [4] Single-Molecule Profiling of Ribosome Recoding Phenomena
    Chen, Jin
    Puglisi, Joseph D.
    BIOPHYSICAL JOURNAL, 2015, 108 (02) : 391A - 391A
  • [5] Single-Molecule Analysis of Ribosome and Factor Assembly Pathways on a Viral mRNA
    Johnson, Alex G.
    Puglisi, Joseph D.
    BIOPHYSICAL JOURNAL, 2018, 114 (03) : 595A - 595A
  • [6] Resolving chaperone action on ribosome-bound nascent chains with single-molecule spectroscopy
    Rajasekaran, Nandakumar
    Liao, Ting-Wei
    Ha, Taekjip
    Kaiser, Christian
    PROTEIN SCIENCE, 2023, 32 (12)
  • [7] Resolving chaperone action on ribosome-bound nascent chains with single-molecule spectroscopy
    Rajasekaran, Nandakumar
    Liao, Ting-Wei
    Ha, Taekjip
    Kaiser, Christian M.
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 204A - 204A
  • [8] Mass Action at the Single-Molecule Level
    Shon, Min Ju
    Cohen, Adam E.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (35) : 14618 - 14623
  • [9] Chaperone Action at the Single-Molecule Level
    Mashaghi, Alireza
    Kramer, Guenter
    Lamb, Don C.
    Mayer, Matthias P.
    Tans, Sander J.
    CHEMICAL REVIEWS, 2014, 114 (01) : 660 - 676
  • [10] Single-molecule Fluorescence Microscopy Study Of The Ribosome Translation Process
    Dulin, David
    Perronet, Karen
    Westbrook, Nathalie
    Bouyer, Philippe
    Soler, Nicolas
    Fourmy, Dominique
    Yoshizawa, Satoko
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 579A - 580A
12345