Taxanes in the treatment of advanced (stage III and IV) non-small cell lung cancer (NSCLC): Recent developments

被引：16
|
作者：
Simon, GR
Bunn, PA
机构：
[1] Univ S Florida, Coll Med, H Lee Moffitt Canc Ctr & Res Inst, Thorac Oncol Program, Tampa, FL 33612 USA
[2] Univ Colorado, Hlth Sci Ctr, Denver, CO USA
来源：
CANCER INVESTIGATION | 2003年 / 21卷 / 01期
关键词：
non-small cell lung cancer; chemotherapy; radiaion therapy; cisplatin; carboplatin; paclitaxel; docetaxel; gemcitabine; vinorelbine;
D O I：
10.1081/CNV-120005919
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Taxanes, paclitaxel. and docetaxel have become the cornerstone of both first-line and second-line chemotherapy for advanced non-small cell lung cancer (NSCLC). Recently, several pivotal phase III randomized trials have been published. These studies and phase II trials will be discussed. Additionally, studies utilizing a taxane and radiation therapy for resectable and locally advanced NSCLC will be outlined. The article will end with a discussion on newer strategies being currently explored to improve survival in advanced NSCLC.
引用
收藏
页码：87 / 104
页数：18
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