JQ1 suppress Th17 effectors by blocking p300-mediated acetylation of RORγt

被引：0

作者：

Zhang, Y. ^{[1
]}

Wang, X. ^{[1
]}

Xia, Y. ^{[1
]}

Yang, Y. ^{[1
]}

Ren, D. ^{[1
]}

Wu, Q. ^{[1
]}

Liu, M. ^{[1
]}

Ren, C. ^{[1
]}

Li, B. ^{[2
]}

Shen, J. ^{[1
]}

机构：

[1] Anhui Med Univ, Hefei, Anhui, Peoples R China

[2] Chinese Acad Sci, Inst Pasteur Shanghai, Shanghai Inst Biol Sci, Hefei, Anhui, Peoples R China

来源：

EUROPEAN JOURNAL OF IMMUNOLOGY | 2019年 / 49卷

关键词：

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

P0702

引用

页码：413 / 413

页数：1

共 50 条

[1] JQ1, a bromodomain inhibitor, suppresses Th17 effectors by blocking p300-mediated acetylation of RORγt
Wang, Xiunan
Yang, Yan
Ren, Dandan
Xia, Yuanyuan
He, Wenguang
Wu, Qingsi
Zhang, Junling
Liu, Miao
Du, Yinan
Ren, Cuiping
Li, Bin
Shen, Jijia
Zhang, Yuxia
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 177 (13) : 2959 - 2973
[2] Autoreactive memory Th17 cells are principally derived from T-bet+ROR?t+ Th17/1 effectors
Fan, Nai-Wen
Wang, Shudan
Ortiz, Gustavo
Chauhan, Sunil K.
Chen, Yihe
Dana, Reza
JOURNAL OF AUTOIMMUNITY, 2022, 129
[3] p300-Mediated Acetylation Stabilizes the Th-Inducing POK Factor
Zhang, Min
Zhang, Jiali
Rui, Jinxiu
Liu, Xiaolong
JOURNAL OF IMMUNOLOGY, 2010, 185 (07): : 3960 - 3969
[4] Bob1 enhances RORγt-mediated IL-17A expression in Th17 cells through interaction with RORγt
Ikegami, Ippei
Takaki, Hiromi
Kamiya, Shiori
Kamekura, Ryuta
Ichimiya, Shingo
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 514 (04) : 1167 - 1171
[5] Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
Jun R. Huh
Monica W. L. Leung
Pengxiang Huang
Daniel A. Ryan
Michael R. Krout
Raghu R. V. Malapaka
Jonathan Chow
Nicolas Manel
Maria Ciofani
Sangwon V. Kim
Adolfo Cuesta
Fabio R. Santori
Juan J. Lafaille
H. Eric Xu
David Y. Gin
Fraydoon Rastinejad
Dan R. Littman
Nature, 2011, 472 : 486 - 490
[6] RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel disease
de Wit, Jelle
Al-Mossawi, M. Hussein
Huehn, Michael H.
Arancibia-Carcamo, Carolina V.
Doig, Karen
Kendrick, Benjamin
Gundle, Roger
Taylor, Peter
Mcclanahan, Terri
Murphy, Erin
Zhang, Hongjun
Barr, Ken
Miller, J. Richard
Hu, Xiao
Aicher, Thomas D.
Morgan, Rodney W.
Glick, Gary D.
Zaller, Dennis
Correll, Craig
Powrie, Fiona
Bowness, Paul
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 137 (03) : 960 - 963
[7] Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
Huh, Jun R.
Leung, Monica W. L.
Huang, Pengxiang
Ryan, Daniel A.
Krout, Michael R.
Malapaka, Raghu R. V.
Chow, Jonathan
Manel, Nicolas
Ciofani, Maria
Kim, Sangwon V.
Cuesta, Adolfo
Santori, Fabio R.
Lafaille, Juan J.
Xu, H. Eric
Gin, David Y.
Rastinejad, Fraydoon
Littman, Dan R.
NATURE, 2011, 472 (7344) : 486 - 490
[8] IL-17A promotes the proliferation of human nasopharyngeal carcinoma cells through p300-mediated Akt1 acetylation
Cai, Kemin
Wang, Bing
Dou, Hongmei
Luan, Ronglan
Bao, Xueli
Chu, Jiusheng
ONCOLOGY LETTERS, 2017, 13 (06) : 4238 - 4244
[9] AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues
Yamaguchi, Y
Kurokawa, M
Imai, Y
Izutsu, K
Asai, T
Ichikawa, M
Yamamoto, G
Nitta, E
Yamagata, T
Sasaki, K
Mitani, K
Ogawa, S
Chiba, S
Hirai, H
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (15) : 15630 - 15638
[10] The immunomodulatory effects of TNF-α inhibitors on human Th17 cells via RORγt histone acetylation
Lin, Yi-Ching
Lin, Yu-Chih
Wu, Cheng-Chin
Huang, Ming-Yii
Tsai, Wen-Chan
Hung, Chih-Hsing
Kuo, Po-Lin
ONCOTARGET, 2017, 8 (05) : 7559 - 7571

← 1 2 3 4 5 →