Group B streptococcal cellulitis in infancy

Cellulitis in an infant younger than 3 months is most commonly caused by group B streptococci (GBS). A baby with cellulitis in this age group should have a full septic workup including blood and cerebrospinal fluid cultures, as GBS cellulitis may be associated with bacteremia. We discuss a 6-week-old baby with cellulitis and meningitis to illustrate the potential complexity of this infectious disease process. We also present a concise review of GBS cellulitis and of meningitis with initially normal cerebrospinal fluid analysis.