The oral cavity in leprosy: what clinicians need to know

被引：14

作者：

Rodrigues, G. A. ^{[1
]}

Qualio, N. P. ^{[1
]}

de Macedo, L. D. ^{[2
]}

Innocentini, L. M. A. R. ^{[2
]}

Ribeiro-Silva, A. ^{[3
]}

Foss, N. T. ^{[4
]}

Frade, M. A. C. ^{[4
]}

Motta, A. C. F. ^{[1
]}

机构：

[1] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Stomatol Publ Oral Hlth & Forens Dent, Oral Diag Div, Ribeirao Preto, SP, Brazil

[2] Univ Sao Paulo, Ribeirao Preto Sch Med, Dent & Stomatol Div, Ribeirao Preto Clin Hosp, Ribeirao Preto, SP, Brazil

[3] Univ Sao Paulo, Ribeirao Preto Sch Med, Dept Pathol & Forens Med, Ribeirao Preto, SP, Brazil

[4] Univ Sao Paulo, Ribeirao Preto Sch Med, Div Dermatol, Dept Internal Med, Ribeirao Preto, SP, Brazil

来源：

ORAL DISEASES | 2017年 / 23卷 / 06期

基金：

巴西圣保罗研究基金会;

关键词：

leprosy; Mycobacterium leprae; oral cavity; reactional episodes; immunology; saliva; MYCOBACTERIUM-LEPRAE; OROFACIAL MANIFESTATIONS; LEPROMATOUS LEPROSY; DIAGNOSIS; LESIONS; INFECTION; GRANULOMATOSIS; SERODIAGNOSIS; EPIDEMIOLOGY; INVOLVEMENT;

D O I：

10.1111/odi.12582

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a bacillus that has a tropism for skin and peripheral nerves. Leprosy treatment is based on a multidrug therapy established by the World Health Organization in 1982 and, despite its widespread use, Brazil ranks second worldwide in numbers of cases. Oral involvement in leprosy has been poorly described in the literature, and few studies have shown that although the bacillus is found in mucosa, specific leprosy lesions are rare and affect patients with advanced stages of the disease. This review aimed to assess the literature on oral manifestations in leprosy and the aspects involving oral cavity in leprosy pathogenesis.

引用

页码：749 / 756

页数：8

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