Excision alone for small size ductal carcinoma in situ of the breast

被引：10

作者：

Kim, Haeyoung ^{[1
]}

Noh, Jae Myoung ^{[2
]}

Choi, Doo Ho ^{[2
]}

Lee, Jihye ^{[3
]}

Nam, Seok Jin ^{[4
]}

Lee, Jeong Eon ^{[4
]}

Park, Won ^{[3
]}

Huh, Seung Jae ^{[3
]}

机构：

[1] Hallym Univ, Dongtan Sacred Heart Hosp, Dept Radiat Oncol, Seoul, South Korea

[2] Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Radiat Oncol, Seoul 135710, South Korea

[3] Ewha Womans Univ, Med Ctr, Dept Radiat Oncol, Seoul, South Korea

[4] Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Surg, Seoul 135710, South Korea

来源：

BREAST | 2014年 / 23卷 / 05期

关键词：

Intraductal carcinoma; Breast; Surgery; Radiotherapy; NUYS PROGNOSTIC INDEX; LOCAL RECURRENCE; TUMOR RECURRENCES; RISK; WOMEN; CLASSIFICATION; RADIOTHERAPY; UNIVERSITY; TAMOXIFEN; NOMOGRAM;

D O I：

10.1016/j.breast.2014.05.025

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This study was performed to determine the risk of tumor recurrence after local excision alone in patients with small size (<= 1 cm) ductal carcinoma in situ ( DCIS) of the breast. We have treated 107 patients who had DCIS measuring <= 1 cm with margin widths of >= 0.3 cm with excision alone per institutional protocol. With a median follow-up time of 58 months, 4 patients developed ipsilateral breast tumor recurrence ( IBTR). Two of the 4 recurrences were invasive, whereas 2 were DCIS. The 5-year rate of IBTR was 6.1%. The patients with resection margin of <1.0 cm had significantly higher rate of IBTR than the patients with resection margin of >= 1.0 cm (23.1% vs. 1.5% at 5-year, p < 0.01). In conclusion, radiotherapy is necessary in the patients with resection margin of <1.0 cm after excision alone because of the substantial risk of IBTR. (C) 2014 Published by Elsevier Ltd.

引用

页码：586 / 590

页数：5

共 50 条

[1] Wide excision alone for ductal carcinoma in situ (DCIS) of the breast
Wong, JS
Gadd, MA
Gelman, R
Kaelin, CM
Lester, S
Schnitt, SJ
Sgroi, DC
Smith, BL
Troyan, SL
Harris, JR
[J]. BREAST CANCER RESEARCH AND TREATMENT, 2003, 82 : S10 - S10
[2] Local excision alone for patients with small size ductal carcinoma-in-situ of the breast: A Korean single institutional experience
Kim, H.
Noh, J. M.
Lee, J.
Choi, D. H.
Nam, S. J.
Lee, J. E.
Park, W.
Huh, S. J.
[J]. EUROPEAN JOURNAL OF CANCER, 2013, 49 : S460 - S460
[3] Prospective study of wide excision alone for ductal carcinoma in situ of the breast
Wong, JS
Kaelin, CM
Troyan, SL
Gadd, MA
Gelman, R
Lester, SC
Schnitt, SJ
Sgroi, DC
Silver, BJ
Harris, JR
Smith, BL
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (07) : 1031 - 1036
[4] Prospective study of wide excision alone for ductal carcinoma in situ of the breast
Lagios, Michael D.
Page, David L.
Silverstein, Melvin J.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (23) : 3809 - 3811
[5] Small size ductal carcinoma in situ of the breast: Predictors of positive margins after local excision
de Roos, Marnix A.
Groote, Alex D.
Pijnappel, Ruud M.
Post, Wendy J.
de Vries, Jaap
Baas, Peter C.
[J]. INTERNATIONAL SURGERY, 2006, 91 (02) : 100 - 106
[6] Recurrence of breast cancer following local excision alone for ductal carcinoma in situ
Horiguchi J.
Iino Y.
Takei H.
Maemura M.
Koibuchi Y.
Horii Y.
Matsumoto H.
Yokoe T.
Oyama T.
Nakajima T.
Morishita Y.
[J]. Breast Cancer, 2001, 8 (1) : 52 - 57
[7] Ductal carcinoma in situ of the breast: 11 reasons to consider treatment with excision alone
Silverstein, Melvin J.
[J]. WOMENS HEALTH, 2008, 4 (06) : 565 - 577
[8] Prospective study of wide excision alone for ductal carcinoma in situ of the breast - Reply
Wong, Julia S.
Lester, Susan C.
Smith, Barbara L.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (23) : 3811 - 3812
[9] A retrospective review of wide excision alone for ductal carcinoma in situ (DCIS) of the breast.
Mitra, SS
Salman, A
Bloomfield, D
Johri, A
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (14) : 73S - 73S
[10] Is excision alone adequate treatment for low-risk ductal carcinoma-in-situ of the breast?
Solin, LJ
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (07) : 1017 - 1019

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