Hydration of Biopolymer-Chlorophyllin Complexes Measured by Microwave Differential Dielectrometry

被引：0

作者：

Pesina, Daryna ^{[1
]}

Khorunzhaya, Olga ^{[1
]}

Kashpur, Vsevolod ^{[1
]}

Shestopalova, Anna ^{[1
]}

Maleev, Vladimir ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, O Ya Usikov Inst Radiophys & Elect, Dept Biol Phys, Kharkov, Ukraine

来源：

2015 45TH EUROPEAN MICROWAVE CONFERENCE (EUMC) | 2015年

关键词：

hydration; DNA; serum albumin; chlorophyllin; complex dielectric permittivity; EHF dielectrometry; SERUM-ALBUMIN; FATTY-ACIDS; BINDING; WATER;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We show that the microwave differential dielectrometry can be used to investigate biopolymer-drug complexation. The present study was designed to examine the hydration effects accompanying the interaction between chlorophyllin, a potent inhibitor of carcinogenesis, and its possible biopolymer targets: DNA and plasma proteins (human and bovine serum albumins) in aqueous solutions. We show that for all complexes the process of complex formation is accompanied by changes of dielectric parameters. We also present calculations of the hydration of the investigated biopolymers and their complexes with ligand, which were carried out basing on model concepts.

引用

页码：991 / 994

页数：4

共 10 条

[1] INVESTIGATION OF HYDRATION OF GLOBULAR PROTEINS BY DIFFERENTIAL DIELECTROMETRY
KASHPUR, VA
MALEEV, VY
SHCHEGOLEVA, TY
MOLECULAR BIOLOGY, 1976, 10 (03) : 462 - 469
[2] Dielectric properties and hydration of human and bovine serum albumin complexes with chlorophyllin
Pesina, D. A.
Khorunzhaya, O. V.
Kashpur, V. A.
Shestopalova, A. V.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2013, 42 : S180 - S180
[3] MONITORING OF THE ENZYMATIC REACTIONS COURSE BY DIFFERENTIAL MICROWAVE DIELECTROMETRY METHOD IN REAL TIME
Kuznetsova, K. S.
Pashynska, V. A.
Eremenko, Z. E.
Shubnyi, O. I.
Martynov, A. V.
Prokopenko, A. A.
UKRAINIAN JOURNAL OF PHYSICS, 2023, 68 (09): : 608 - 618
[4] INFLUENCE OF XENON ON PROTEIN HYDRATION AS MEASURED BY MICROWAVE ABSORPTION TECHNIQUE
SCHOENBORN, BP
VOGELHUT, PO
SUSSKIND, C
FEATHERSTONE, RM
NATURE, 1964, 202 (493) : 695 - &
[5] Hydration and swelling of pulp fibers measured with differential scanning calorimetry
Maloney, TC
Paulapuro, H
Stenius, P
NORDIC PULP & PAPER RESEARCH JOURNAL, 1998, 13 (01) : 31 - 36
[6] EFFECT OF HYDRATION ON THERMAL-DENATURATION OF LYSOZYME AS MEASURED BY DIFFERENTIAL SCANNING CALORIMETRY
FUJITA, Y
NODA, Y
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1978, 51 (05) : 1567 - 1568
[7] THE EFFECT OF HYDRATION ON THE THERMAL-STABILITY OF OVALBUMIN AS MEASURED BY MEANS OF DIFFERENTIAL SCANNING CALORIMETRY
FUJITA, Y
NODA, Y
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1981, 54 (10) : 3233 - 3234
[8] EFFECT OF HYDRATION ON THE THERMAL-STABILITY OF PROTEIN AS MEASURED BY DIFFERENTIAL SCANNING CALORIMETRY - CHYMOTRYPSINOGEN-A
FUJITA, Y
NODA, Y
INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1981, 18 (01): : 12 - 17
[9] EFFECT OF HYDRATION ON THE THERMAL-STABILITY OF PROTEIN AS MEASURED BY DIFFERENTIAL SCANNING CALORIMETRY - LYSOZYME-D2O SYSTEM
FUJITA, Y
NODA, Y
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1979, 52 (08) : 2349 - 2352
[10] Hydration effect on solid DNA-didecyldimethylammonium chloride complexes measured using 1H-nuclear magnetic resonance spectroscopy
Niziol, J.
Haranczyk, H.
Kobierski, J.
Hebda, E.
Pielichowski, J.
Ostachowicz, B.
JOURNAL OF APPLIED PHYSICS, 2013, 114 (14)

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