Bilateral Conjunctival Melanocytic Nevi of Simultaneous Onset Simulating Conjunctivitis in a Child
被引:4
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作者:
Jakobiec, Frederick A.
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Massachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USAMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Boston, MA 02114 USA
Jakobiec, Frederick A.
[1
,2
]
Sandhu, Harpal
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Harvard Univ, Sch Med, Boston, MA USAMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Boston, MA 02114 USA
Sandhu, Harpal
[2
]
Bhat, Pooja
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机构:
Massachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USAMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Boston, MA 02114 USA
Bhat, Pooja
[1
,2
]
Colby, Kathryn
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机构:
Harvard Univ, Sch Med, Boston, MA USA
Massachusetts Eye & Ear Infirm, Cornea Serv, Dept Ophthalmol, Boston, MA 02114 USAMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Boston, MA 02114 USA
Colby, Kathryn
[2
,3
]
机构:
[1] Massachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] Massachusetts Eye & Ear Infirm, Cornea Serv, Dept Ophthalmol, Boston, MA 02114 USA
A healthy 10-year-old girl developed synchronous, bilateral, temporal redness of the eyes regarded as sectoral conjunctivitis for 5 years that was unresponsive to topical steroids and antihistamines. Finely vascularized, minimally elevated, amelanotic or faintly focally pigmented, epibulbar conjunctival lesions were present bilaterally. The lesions were completely excised. Histopathologic and immunohistochemical evaluations confirmed that they were both predominantly junctional nevi with conspicuous chronic inflammation. Juvenile conjunctival nevi frequently have atypical histopathologic traits that in an adult could be suggestive of melanoma. The differential diagnosis of much less likely disorders includes leukemia, lymphoid tumor (salmon patch), and conjunctival sarcoidosis, among other conditions. The patient has had no recurrence 3 years after surgery.
机构:
Thomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USAThomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USA
Eagle, Ralph C.
Lally, Sara E.
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Thomas Jefferson Univ, Wills Eye Hosp, Ocular Oncol Serv, Philadelphia, PA 19107 USAThomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USA
Lally, Sara E.
Shields, Carol L.
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Thomas Jefferson Univ, Wills Eye Hosp, Ocular Oncol Serv, Philadelphia, PA 19107 USAThomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USA
Shields, Carol L.
Shields, Jerry A.
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Thomas Jefferson Univ, Wills Eye Hosp, Ocular Oncol Serv, Philadelphia, PA 19107 USAThomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USA
Shields, Jerry A.
Langer, Paul D.
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Rutgers State Univ, Inst Ophthalmol & Visual Sci, Newark, NJ USAThomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USA
Langer, Paul D.
Sheehan, Joseph
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Univ Washington, Dept Ophthalmol, Seattle, WA 98195 USAThomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USA
Sheehan, Joseph
Milman, Tatyana
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Thomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USA
Thomas Jefferson Univ, Dept Pathol Anat & Cell Biol, Philadelphia, PA 19107 USAThomas Jefferson Univ, Wills Eye Hosp, Dept Ophthalm Pathol, Philadelphia, PA 19107 USA
机构:
Massachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Dept Ophthalmol, Boston, MA 02114 USAMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Dept Ophthalmol, Boston, MA 02114 USA
Jakobiec, Frederick A.
Colby, Kathryn
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Massachusetts Eye & Ear Infirm, Cornea Serv, Boston, MA 02114 USAMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Dept Ophthalmol, Boston, MA 02114 USA
Colby, Kathryn
Bajart, Ann M.
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Ophthalm Consultants Boston, Boston, MA USAMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Dept Ophthalmol, Boston, MA 02114 USA
Bajart, Ann M.
Saragas, S. John
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Saragas Eye Ctr, Somerville, MA USAMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Dept Ophthalmol, Boston, MA 02114 USA
Saragas, S. John
Moulin, Alexandre
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Hop Ophtalm Jules Gonin, Lausanne, SwitzerlandMassachusetts Eye & Ear Infirm, David G Cogan Ophthalm Pathol Lab, Dept Ophthalmol, Boston, MA 02114 USA
机构:
Mem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
Weill Cornell Med Ctr, Dept Ophthalmol, New York, NY USAMem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
Francis, Jasmine H.
Grossniklaus, Hans E.
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Emory Univ, Sch Med, Dept Ophthalmol, Atlanta, GA 30322 USAMem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
Grossniklaus, Hans E.
Habib, Larissa A.
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Mem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
Habib, Larissa A.
Marr, Brian
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Mem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
Weill Cornell Med Ctr, Dept Ophthalmol, New York, NY USAMem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
Marr, Brian
Abramson, David H.
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Mem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
Weill Cornell Med Ctr, Dept Ophthalmol, New York, NY USAMem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
Abramson, David H.
Busam, Klaus J.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USA
Weill Cornell Med Ctr, Dept Pathol, New York, NY USAMem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, 1275 York Ave, New York, NY 10021 USA
机构:
Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA
Busam, Klaus J.
Fang, Yuqiang
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Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA
Fang, Yuqiang
Jhanwar, Suresh C.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA
Jhanwar, Suresh C.
Pulitzer, Melissa P.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA
Pulitzer, Melissa P.
Marr, Brian
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Mem Sloan Kettering Canc Ctr, Dept Surg, Ophthalmol Oncol Serv, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA
Marr, Brian
Abramson, David H.
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Mem Sloan Kettering Canc Ctr, Dept Surg, Ophthalmol Oncol Serv, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA
机构:
S China Normal Univ, MOE Key Lab Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China
S China Normal Univ, Lab Photon Chinese Med, Guangzhou 510631, Guangdong, Peoples R ChinaS China Normal Univ, MOE Key Lab Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China
Zhuang, Zhengfei
Ke, Xiong
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So Med Univ, Southern Hosp, Guangzhou, Guangdong, Peoples R ChinaS China Normal Univ, MOE Key Lab Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China
Ke, Xiong
Guo, Zhouyi
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S China Normal Univ, MOE Key Lab Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China
S China Normal Univ, Lab Photon Chinese Med, Guangzhou 510631, Guangdong, Peoples R ChinaS China Normal Univ, MOE Key Lab Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China
Guo, Zhouyi
Chen, Sijin
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So Med Univ, Southern Hosp, Guangzhou, Guangdong, Peoples R ChinaS China Normal Univ, MOE Key Lab Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China
Chen, Sijin
Li, Ning
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S China Normal Univ, MOE Key Lab Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China
S China Normal Univ, Lab Photon Chinese Med, Guangzhou 510631, Guangdong, Peoples R ChinaS China Normal Univ, MOE Key Lab Laser Life Sci, Coll Biophoton, Guangzhou 510631, Guangdong, Peoples R China