Synthesis of polyfunctionalized thiophenes and enediynes via ring-opening reactions of 3-lithiated thieno[2,3-b](and [3,2-b])thiophenes, 3,4-dilithiated thieno[2,3-b]thiophenes and 3,6-dilithiated thieno[3,2-b]thiophenes

被引：13
|
作者：
Fuller, LS
Iddon, B
Smith, KA
机构：
[1] Synthet Chem Ltd, Wolverhampton WV10 7BP, England
[2] Univ Salford, Sci Res Inst, Div Chem Sci, Salford M5 4WT, Lancs, England
来源：
CHEMICAL COMMUNICATIONS | 1997年 / 24期
关键词：
D O I：
10.1039/a707033k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Solutions of the title lithiated thienothiophenes were synthesized from 2,5-disubstituted 3,4-dibromothieno[2,3-b]thiophenes or 3,6-dibromothieno[3,2-b]thiophenes via Br --> Li exchange with 1.0 or 2.0 equiv. of BuLi (THF, -78 degrees C), respectively, and gave either polyfunctionalized thiophenes or polyfunctionalized enediynes (by a novel tandem ring-opening process in these cases) on being allowed to warm up to ambient temperature.
引用
收藏
页码：2355 / 2356
页数：2
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