Treatment of toxic epidermal necrolysis in AIDS with intravenous immunoglobulins

被引:14
|
作者
Tan, A
Tan, HH
Lee, CC
Ng, SK
机构
[1] Natl Skin Ctr, Singapore 308205, Singapore
[2] Tan Tock Seng Hosp, Communicable Dis Ctr, Singapore, Singapore
关键词
D O I
10.1046/j.1365-2230.2003.01255.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Individuals with AIDS are at higher risk of developing severe cutaneous adverse drug reactions. We report two AIDS patients with drug-induced toxic epidermal necrolysis (TEN). The suspected drugs were discontinued. Both patients were treated with intravenous human immunoglobulins at a dose of 1 g/kg body weight per day for two consecutive days and both experienced a good outcome. Intravenous immunoglobulin potentially lowers the morbidity and mortality of TEN and shortens the duration of the patient's hospitalization.
引用
收藏
页码:269 / 271
页数:3
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