At-home compounding preparation of slow desensitization of elexacaftor/tezacaftor/ivacaftor for delayed hypersensitivity rash

被引：7
|
作者：
Muirhead, Corinne [1 ]
Verzasconi, Deborah [1 ]
Joshi, Shyam [2 ]
机构：
[1] Oregon Hlth & Sci Univ, Dept Pharm, 3181 SW Sam Jackson Pk Rd Cr9-4, Portland, OR 97239 USA
[2] Oregon Hlth & Sci Univ, Sect Allergy & Immunol, Portland, OR 97239 USA
来源：
PEDIATRIC PULMONOLOGY | 2022年 / 57卷 / 07期
关键词：
cystic fibrosis; desensitization; drug rash; maculopapular eruption; Trikafta;
D O I：
10.1002/ppul.25938
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
As elexacaftor/tezacaftor/ivacaftor has proven to have robust clinical efficacy for eligible persons with cystic fibrosis, desensitization should be offered to those with maculopapular eruption hypersensitivity reactions to achieve tolerance. As presented in this case, if provided with tools for crushing and mixing the medication, a successful escalation protocol can be completed at home without coordinating the help of a compound pharmacy.
引用
收藏
页码：1779 / 1781
页数：3
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