Antidiarrhoeal activity of hot water extract of black tea (Camellia sinensis)

被引：29
|
作者：
Besra, SE [1 ]
Gomes, A [1 ]
Ganguly, DK [1 ]
Vedasiromoni, JR [1 ]
机构：
[1] Indian Inst Chem Biol, Div Pharmacol & Expt Therapeut, Kolkata 700032, W Bengal, India
来源：
PHYTOTHERAPY RESEARCH | 2003年 / 17卷 / 04期
关键词：
Camellia sinensis (L.) O. Kuntze; black tea extract; diarrhoea; rodents; antidiarrhoeal activity;
D O I：
10.1002/ptr.1171
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The effect of a hot water extract of black tea (Camellia sinensis (L.) O. Kuntze, Theaceae) on upper gastrointestinal transit and on diarrhoea was investigated employing conventional rodent models of diarrhoea. Black tea extract was found to possess antidiarrhoeal activity in all the models of diarrhoea used. Naloxone (0.5 mg/kg i.p.) significantly inhibited the antidiarrhoeal activity of the extract as well as loperamide, thus indicating a role of the opioid system in the antidiarrhoeal activity of the extract. Copyright (C) 2003 John Wiley Sons, Ltd.
引用
收藏
页码：380 / 384
页数：5
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