Fibroblast Growth Factor 21 Prevents Diabetic Cardiomyopathy by Attenuating Cardiac Lipotoxicity via Erk1/2-dependent Signaling Pathway in Mice

被引：0
|
作者：
Tan, Yi [1 ]
Zhang, Chi [1 ]
Yan, Xiaoqing [1 ]
Huang, Zhifeng [2 ]
Gu, Junlian [1 ]
Zhou, Shanshan [1 ]
Shao, Minglong [2 ]
Feng, Wenke [1 ]
Li, Xiaokun [2 ]
机构：
[1] Univ Louisville, Louisville, KY 40292 USA
[2] Wenzhou Med Univ, Wenzhou, Peoples R China
来源：
CIRCULATION RESEARCH | 2015年 / 117卷
关键词：
Fibroblast growth factor 21; Diabetic cardiomyopathy; Cardiac lipotoxicity;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
26
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Fibroblast growth factor 21 is expressed in and protects the diabetic heart from cell death and cardiomyopathy via the Erk1/2-dependent signalling pathway
    Zhang, Chi
    Lu, Xuemian
    Tan, Yi
    Cai, Lu
    [J]. DIABETES-METABOLISM RESEARCH AND REVIEWS, 2014, 30 : 10 - 11
  • [2] Basic fibroblast growth factor stimulates the proliferation of human dermal fibroblast via activation of ERK1/2-dependent pathway
    Makino, T.
    Jhono, T.
    Zhang, X.
    Wakasugi, S.
    Inoue, Y.
    Ihn, H.
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2008, 128 : S136 - S136
  • [3] ERK1/2-Dependent Vascular Endothelial Growth Factor Signaling Sustains Cyst Growth in Polycystin-2 Defective Mice
    Spirli, Carlo
    Okolicsanyi, Stefano
    Fiorotto, Romina
    Fabris, Luca
    Cadamuro, Massimiliano
    Lecchi, Silvia
    Tian, Xin
    Somlo, Stefan
    Strazzabosco, Mario
    [J]. GASTROENTEROLOGY, 2010, 138 (01) : 360 - 371
  • [4] LPS regulate ERK1/2-dependent signaling in cardiac fibroblasts via PKC-mediated MKP-1 induction
    Stawowy, P
    Goetze, S
    Margeta, C
    Fleck, E
    Graf, K
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 303 (01) : 74 - 80
  • [5] Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway
    Zhang, Chi
    Huang, Zhifeng
    Gu, Junlian
    Yan, Xiaoqing
    Lu, Xuemian
    Zhou, Shanshan
    Wang, Shudong
    Shao, Minglong
    Zhang, Fangfang
    Cheng, Peng
    Feng, Wenke
    Tan, Yi
    Li, Xiaokun
    [J]. DIABETOLOGIA, 2015, 58 (08) : 1937 - 1948
  • [6] Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway
    Chi Zhang
    Zhifeng Huang
    Junlian Gu
    Xiaoqing Yan
    Xuemian Lu
    Shanshan Zhou
    Shudong Wang
    Minglong Shao
    Fangfang Zhang
    Peng Cheng
    Wenke Feng
    Yi Tan
    Xiaokun Li
    [J]. Diabetologia, 2015, 58 : 1937 - 1948
  • [7] Urotensin-2 promotes collagen synthesis via ERK1/2-dependent and ERK1/2-independent TGF-β1 in neonatal cardiac fibroblasts
    Dai, Hong-Yan
    He, Tao
    Li, Xiao-Lu
    Xu, Wen-Liang
    Ge, Zhi-Ming
    [J]. CELL BIOLOGY INTERNATIONAL, 2011, 35 (02) : 93 - 98
  • [8] Silenced miR-21 inhibits renal interstitial fibrosis via targeting ERK1/2 signaling pathway in mice
    Tang, C-R.
    Luo, S-G.
    Lin, X.
    Wang, J.
    Liu, Y.
    [J]. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2019, 23 : 110 - 116
  • [9] Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia
    Andres, Christine
    Hasenauer, Jan
    Ahn, Hye-Sook
    Joseph, Elizabeth K.
    Isensee, Joerg
    Theis, Fabian J.
    Allgoewer, Frank
    Levine, Jon D.
    Dib-Hajj, Sulayman D.
    Waxman, Stephen G.
    Hucho, Tim
    [J]. PAIN, 2013, 154 (10) : 2216 - 2226
  • [10] Fibroblast growth factor receptor 1 regulates the differentiation and activation of osteoclasts through Erk1/2 pathway
    Lu, Xiumin
    Su, Nan
    Yang, Jing
    Huang, Wei
    Li, Can
    Zhao, Ling
    He, Qifen
    Du, Xiaolan
    Shen, Yue
    Chen, Bo
    Chen, Lin
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 390 (03) : 494 - 499
12345