Parallelization of Dielectric Measurements at Microwaves for Microfluidic Biosensor Arrays

被引:0
|
作者
Schuessler, M. [1 ]
Puentes, M. [1 ]
Jakoby, R. [1 ]
Dubuc, D. [2 ]
Grenier, K. [2 ]
机构
[1] Tech Univ Darmstadt, Inst Microwave Engn & Photon, Merckstr 25, D-64283 Darmstadt, Germany
[2] CNRS, LAAS, Fluid High Frequency Micro & Nanosyst Grp, F-31077 Toulouse 4, France
关键词
Microwave; biosensor; biological cell; dielectric spectroscopy; IMPEDANCE SPECTROSCOPY;
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
An approach for the parallelization of dielectric measurements at microwaves within a lab-on-a-chip environment is presented. Its targeted application is the simultaneous monitoring of a cell suspension in microfluidic channel arrays under the influence of different drugs e.g. for an effectiveness assessment. The method has the advantage that only a single network analyzer and no other microwave components like switches or multiplexers are necessary. The paper presents the concept of the measurement system, prototype sensors, and their characterization. The realized devices operate between 20 and 25 GHz and have been tested with water, water-ethanol mixtures and Chinese Hamster Ovary (CHO) cells.
引用
收藏
页码:833 / 836
页数:4
相关论文
共 50 条
  • [1] ON DIELECTRIC LOSSES AT MICROWAVES - SENSITIVE MEASUREMENTS AND RESULTS
    BETHE, K
    VERWEEL, J
    IEEE TRANSACTIONS ON MAGNETICS, 1969, MAG5 (03) : 474 - &
  • [2] MEASUREMENTS OF THE COMPLEX DIELECTRIC CONSTANT OF GASES AT MICROWAVES
    LYONS, H
    BIRNBAUM, G
    KRYDER, SJ
    PHYSICAL REVIEW, 1948, 74 (09): : 1210 - 1210
  • [3] DIELECTRIC MEASUREMENTS OF FATTY ACIDS AT MICROWAVES FREQUENCIES.
    Arora, R.P.
    Joshi, S.C.
    1978, 16 (08): : 792 - 794
  • [4] Simultaneous Dielectric Monitoring of Microfluidic Channels at Microwaves Utilizing a Metamaterial Transmission Line Structure
    Schuessler, M.
    Puentes, M.
    Dubuc, D.
    Grenier, K.
    Jakoby, R.
    2012 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2012, : 6273 - 6276
  • [5] PLANAR CONDENSER CAPACITY AND DIELECTRIC LOSSES MEASUREMENTS ON A SEGNETOELECTRIC FILM IN MICROWAVES
    GAIDUKOV, MM
    KOZYREV, AB
    RUBAN, AS
    TERMARTIROSYAN, LT
    VERBITSKAYA, TN
    RADIOTEKHNIKA I ELEKTRONIKA, 1975, 20 (12): : 2588 - 2591
  • [6] Immobilization strategy of liposome modified cantilever biosensor arrays combined with microfluidic channels
    Werner, Carl Frederik
    Takahashi, Yuya
    Mitobe, Ryusuke
    Sohgawa, Masayuki
    Noda, Minoru
    2023 IEEE BIOSENSORS CONFERENCE, BIOSENSORS, 2023,
  • [7] Measurements Of The Liquids Dielectric Properties Changes With Temperature For Microwaves Power Processing Optimization
    Surducan, E.
    Surducan, V.
    Neamtu, C.
    PROCESSES IN ISOTOPES AND MOLECULES (PIM 2011), 2012, 1425 : 85 - 88
  • [8] Integration of Vertical Grating Couplers and Microfluidic Channels with Silicon Photonic Wire Biosensor Arrays
    Densmore, A.
    Xu, D. -X.
    Cheben, P.
    Vachon, M.
    Janz, S.
    Ma, R.
    Bedard, D.
    Li, Y.
    Lopinski, G.
    Delage, A.
    Schmid, J. H.
    Halir, R.
    Molina-Fernandez, I.
    2010 IEEE SENSORS, 2010, : 1550 - 1553
  • [9] Graphene nano-ink biosensor arrays on a microfluidic paper for multiplexed detection of metabolites
    Labroo, Pratima
    Cui, Yue
    ANALYTICA CHIMICA ACTA, 2014, 813 : 90 - 96
  • [10] Ansoft HFSS Software Application for the Dielectric and Magnetic Measurements of Ferroelectrics and Related Materials in Microwaves
    Rudys, S.
    Ivanov, M.
    Banys, J.
    FERROELECTRICS, 2012, 430 : 115 - 122