The Importance of Surgical Margins in Prostate Cancer

被引:36
|
作者
Sooriakumaran, Prasanna [1 ]
Dev, Harveer S. [2 ]
Skarecky, Douglas [3 ]
Ahlering, Thomas [3 ]
机构
[1] Univ Oxford, Dept Urol, Oxford, England
[2] Univ Cambridge, Dept Urol, Cambridge, England
[3] Univ Calif Irvine, Dept Urol, 333 City Blvd West,Suite 2100,RT 81, Irvine, CA USA
关键词
positive surgical margins; prostate cancer; radical prostatectomy; robotic; biochemical recurrence; LAPAROSCOPIC RADICAL PROSTATECTOMY; BIOCHEMICAL RECURRENCE; PROGNOSTIC-SIGNIFICANCE; POSITIVE MARGINS; LEARNING-CURVE; RETROPUBIC PROSTATECTOMY; APICAL MARGIN; LOCATION; FAILURE; IMPACT;
D O I
10.1002/jso.24109
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Positive surgical margins (PSM) after radical prostatectomy (RP) are a predictor of biochemical recurrence (BCR), and highly dependent on surgeon, experience, and skill. The length and location PSMs are important, with significant differences between open and robotic RP. The impact of PSMs on BCR remains secondary to other clinico-pathologic variables: Gleason Score, pathologic stage, and baseline PSA. However, lower PSM rates are associated with reduced use of secondary interventions and patient anxiety of cancer recurrence. (c) 2016 Wiley Periodicals, Inc.
引用
收藏
页码:310 / 315
页数:6
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