Next-generation biomarkers for detecting kidney toxicity

被引：396
|
作者：
Bonventre, Joseph V. [1 ]
Vaidya, Vishal S. [1 ]
Schmouder, Robert [2 ]
Feig, Peter [3 ]
Dieterle, Frank [4 ]
机构：
[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Renal,Dept Med, Boston, MA 02115 USA
[2] Novartis Inst BioMed Res, E Hanover, NJ USA
[3] Merck Res Labs, Rahway, NJ USA
[4] Novartis Inst BioMed Res, Basel, Switzerland
来源：
NATURE BIOTECHNOLOGY | 2010年 / 28卷 / 05期
关键词：
INJURY; QUALIFICATION;
D O I：
10.1038/nbt0510-436
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
There is a paucity of biomarkers that reliably detect nephrotoxicity. The Predictive Safety Testing Consortium (PSTC) faced several challenges in identifying novel safety biomarkers in the renal setting.
引用
收藏
页码：436 / 440
页数：5
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