Resveratrol effects in bladder cancer: A mini review

被引：0
|
作者：
Almeida, Tamires Cunha [1 ]
da Silva, Glenda Nicioli [1 ]
机构：
[1] Univ Fed Ouro Preto, Lab Pesquisas Clin, Ouro Preto, MG, Brazil
来源：
GENETICS AND MOLECULAR BIOLOGY | 2021年 / 44卷 / 01期
关键词：
Apoptosis; bladder cancer; cell cycle arrest; cell signalling; resveratrol; IN-VITRO; TRANS-RESVERATROL; HEALTHY-VOLUNTEERS; DRUG-RESISTANCE; KINASE; APOPTOSIS; CELLS; INDUCTION; INHIBITION; EXPRESSION;
D O I：
10.1590/1678-4685-GMB-2020-0371
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bladder cancer has a high incidence worldwide and is the most common genitourinary cancer. The treatment of bladder cancer involves surgery and chemotherapy; however high failure rates and toxicity are observed. In this context, the search of new drugs aiming a more effective treatment is extremely necessary. Natural products are an important source of compounds with antiproliferative effects. Resveratrol is a naturally occurring plant polyphenol whose anticancer activity has been demonstrated in different types of cancer. This review summarizes the in vitro and in vivo studies using models of bladder cancer treated with resveratrol and discusses its different mechanisms of action.
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页数：8
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