Bioaccumulation of PAHs and Their Hydroxylated Metabolites in Common Carp (Cyprinus Carpio Linnaeus 1758) in Controlled Environment

被引:15
|
作者
Lazartigues, A. [1 ]
Thomas, M. [1 ]
Brun-Bellut, J. [1 ]
Feidt, C. [1 ]
机构
[1] Nancy Univ, UR AFPA, INRA, F-54500 Vandoeuvre Les Nancy, France
关键词
POLYCYCLIC AROMATIC-HYDROCARBONS; EDIBLE FISH; SEDIMENTS; RIVER; CYTOCHROME-P4501A; INDUCTION; CAMARGUE; RESERVE; BILE;
D O I
10.1080/10406631003756187
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This study aimed to determine the incorporation of PAHs into muscle of Cyprinus carpio. Three model compounds (phenanthrene, pyrene and benzo[a]pyrene) were orally administered during 56 days, in a series of three increasing doses (0, 100, 500 g of each PAHs per kg of fish). PAHs and their hydroxylated metabolites were analyzed by a HPLC-Fluorimetry method. Results of this study showed a significant increase of phenanthrene and pyrene in muscle. Benzo[a]pyrene incorporation to muscle was not effective. Concerning hydroxylated metabolites, they were not detected in muscle of carp. Steady states for phenanthrene and pyrene were obtained after 28 days of exposure. Low incorporation to muscle was observed at equilibrium for phenanthrene (6% and 3%) and pyrene (3% and 1%), depending of the dose tested.
引用
收藏
页码:141 / 152
页数:12
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