Nonsteroidal anti-inflammatory drugs in cats: a review

被引：117
|
作者：
Duncan, B. [1 ]
Lascelles, X.
Court, Michael H.
Hardie, Elizabeth M.
Robertson, Sheilah A.
机构：
[1] N Carolina State Univ, Dept Clin Sci, Comparat Pain Res Lab, Raleigh, NC 27695 USA
[2] Tufts Univ, Sch Med, Dept Pharmacol & Expt Therapeut, Boston, MA USA
[3] Univ Florida, Dept Large Anim Clin Sci, Gainesville, FL USA
来源：
VETERINARY ANAESTHESIA AND ANALGESIA | 2007年 / 34卷 / 04期
关键词：
cat; kinetics; non-steroidal anti-inflammatory drug; pain; pharmacology;
D O I：
10.1111/j.1467-2995.2006.00322.x
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Objective: To review the evidence regarding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in cats Databases used: PubMed, CAB abstracts. Conclusions: Nonsteroidal anti-inflammatory drugs should be used with caution in cats because of their low capacity for hepatic glucuronidation, which is the major mechanism of metabolism and excretion for this category of drugs. However, the evidence presented supports the short-term use of carprofen, flunixin, ketoprofen, meloxicam and tolfenamic acid as analgesics in cats. There were no data to support the safe chronic use of NSAIDs in cats.
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页码：228 / 250
页数：23
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