Combination of RuCl3•xH2O with PEG - a simple and recyclable catalytic system for direct arylation of heteroarenes via C-H bond activation

被引：14

作者：

Jian, Lei ^{[1
]}

He, Hai-Yu ^{[1
]}

Huang, Jin ^{[1
]}

Wu, Qian-Hui ^{[1
]}

Yuan, Mao-Lin ^{[1
]}

Fu, Hai-Yan ^{[1
]}

Zheng, Xue-Li ^{[1
]}

Chen, Hua ^{[1
]}

Li, Rui-Xiang ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem, Key Lab Green Chem & Technol, Minist Educ, Chengdu 610064, Peoples R China

来源：

RSC ADVANCES | 2017年 / 7卷 / 38期

基金：

中国国家自然科学基金;

关键词：

ONE-POT SYNTHESIS; RUTHENIUM(II) CARBOXYLATE; EFFICIENT SYNTHESIS; FUNCTIONALIZATION; ACCESS; WATER; ACIDS; MILD; COMPLEXES; MECHANISM;

D O I：

10.1039/c7ra02638b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and recyclable catalytic system for direct arylation of heteroarenes via C-H bond activation was developed with a relatively inexpensive RuCl3 center dot xH(2)O as a catalyst and PEG-400 as a green medium without any additive or ligand. This system not only showed excellent functional group compatibility, but also the ratio of mono-to diarylated product was easily regulated by varying the reaction conditions. Moreover, this transformation could proceed under air and be easily scaled up to gram-scale in a low catalyst loading of 0.3 mol%. Particularly, a good yield of 85% was obtained after this catalyst was recycled six times.

引用

页码：23515 / 23522

页数：8

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