Composition and antifungal activity of the essential oil of Mentha cervina from Portugal

被引：32
|
作者：
Goncalves, M. J.
Vicente, A. M.
Cavaleiro, C.
Salgueiro, L.
机构：
[1] Univ Coimbra, Fac Farm, CEF, Lab Farmacognosia, P-3000295 Coimbra, Portugal
[2] DRAEDM, P-4700859 Braga, Portugal
来源：
NATURAL PRODUCT RESEARCH | 2007年 / 21卷 / 10期
关键词：
essential oils; Mentha cervina; mint; antifungal activity;
D O I：
10.1080/14786410701482244
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of Mentha cervina collected during the flowering and vegetative phases of the plants were investigated by GC and GC-MS. Quantitative differences were observed in the compositions, particularly in the amounts of pulegone (12.9-79.6%) and isomenthone (8.7-77.0%). Antifungal activity of the oils was evaluated by minimal inhibitory concentrations (MIC) and minimal lethal concentrations (MLC) against Candida, Apergillus and dermatophyte strams. Antifungal activity of the sample containing lower amounts of pulegone was the highest for dermatophytes, particularly for Epidermophyton floccosum with MIC and MLC values of 0.63 mu L mL(-1). Mentha cervina oils with low content of pulegone, may be an alternative as antifungal agents in dermatophytosis.
引用
收藏
页码：867 / 871
页数：5
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