Sample scale-free gene regulatory network using gene ontology

被引:0
|
作者
Chen, Guanrao [1 ]
Larsen, Peter [2 ]
Almasri, Eyad [3 ]
Dai, Yang
机构
[1] Univ Illinois, Dept Comp Sci, Chicago, IL 60607 USA
[2] Univ Illinois, Core Genom Lab, Chicago, IL 60607 USA
[3] Univ Illinois, Dept Bioengn, Chicago, IL 60607 USA
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D O I
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中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Currently there are various approaches to the reconstruction of gene regulatory networks from different sources of data. However, none of these methods incorporates explicitly scale-free property, one of the most important features of the targeted network, into their algorithms. In this paper, several network sampling strategies are explored on a set assembled from previous published gene interactions in yeast, expecting to reconstruct regulatory networks that are scale-free.
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页码:3002 / +
页数:2
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