CSF characteristics in early-onset multiple sclerosis

被引：122
|
作者：
Pohl, D
Rostasy, K
Reiber, H
Hanefeld, F
机构：
[1] Univ Gottingen, Dept Pediat & Pediat Neurol, D-37075 Gottingen, Germany
[2] Univ Gottingen, Dept Neurol, Neurochem Lab, D-37075 Gottingen, Germany
来源：
NEUROLOGY | 2004年 / 63卷 / 10期
关键词：
D O I：
10.1212/01.WNL.0000144352.67102.BC
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors studied CSF characteristics in 136 patients with multiple sclerosis ( MS) with a disease onset before age 16. In the initial diagnostic lumbar puncture, CSF-pleocytosis was observed in 66%, blood-CSF barrier dysfunction in 13%, and oligoclonal IgG in 92% of the early-onset MS (EOMS) patients. CSF oligoclonal IgG supports the early diagnosis of MS in childhood with a sensitivity similar to adult-onset MS.
引用
收藏
页码：1966 / 1967
页数：2
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