Pictorial review on abdominal applications of ferumoxytol in MR imaging

被引:8
|
作者
Kordbacheh, Hamed [1 ]
Baliyan, Vinit [2 ]
Parakh, Anushri [1 ]
Wojtkiewicz, Gregory R. [3 ]
Hedgire, Sandeep [2 ]
Harisinghani, Mukesh G. [1 ]
机构
[1] Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiol, 55 Fruit St,White 270, Boston, MA 02114 USA
[2] Harvard Med Sch, Massachusetts Gen Hosp, Div Cardiovasc Imaging, Boston, MA 02115 USA
[3] Harvard Med Sch, Massachusetts Gen Hosp, Ctr Syst Biol, Boston, MA 02115 USA
关键词
Magnetic resonance imaging; Ferumoxytol; USPIO; Contrast media; SUPERPARAMAGNETIC IRON-OXIDE; AORTIC-VALVE-REPLACEMENT; PANCREATIC INFLAMMATION; DEFICIENCY ANEMIA; LYMPH-NODES; CONTRAST AGENT; SAFETY; NANOPARTICLE; FERUMOXTRAN-10; CANCER;
D O I
10.1007/s00261-019-02163-4
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Though gadolinium-based contrast agents are the most widely used contrast media in MR for clinical use, problems with nephrogenic systemic fibrosis and tissue deposition render their safety debatable, at least in a selected patient population. Ferumoxytol has the potential to be used as an alternate contrast medium for various clinical applications across multiple organs. It has prolonged intravascular signal and delayed intracellular macrophage uptake which are unique properties compared to gadolinium-based agents. This pictorial review aims to review the current and potential clinical applications of ferumoxytol as a contrast agent in abdominal MR imaging.
引用
收藏
页码:3273 / 3284
页数:12
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