Use of Tofacitinib for the Treatment of Arthritis Associated With Ulcerative Colitis

被引：11
|
作者：
Wang, Wenfei [1 ]
Cleveland, Noa Krugliak [2 ]
Ollech, Jacob [2 ]
Rubin, David T. [2 ]
机构：
[1] Univ Chicago Med, Dept Med, Chicago, IL USA
[2] Univ Chicago Med, Ctr Inflammatory Bowel Dis, Chicago, IL USA
来源：
ACG CASE REPORTS JOURNAL | 2019年 / 6卷 / 09期
关键词：
EXTRAINTESTINAL MANIFESTATIONS; VEDOLIZUMAB THERAPY; PHARMACOKINETICS; INHIBITOR; EFFICACY; PLACEBO; IMPACT; TRIAL;
D O I：
10.14309/crj.0000000000000226
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Tofacitinib is a Janus kinase 1-3 inhibitor initially approved for the treatment of rheumatoid arthritis and now approved for the treatment of moderately to severely active ulcerative colitis (UC). We present the case of a patient with UC and seronegative inflammatory arthritis in whom arthritis progressed while on vedolizumab and was successfully treated with tofacitinib. This case provides insight into the use of tofacitinib for the treatment of UC and a concomitant extraintestinal manifestation of joint involvement.
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页数：3
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