Effect of aestivation of Biomphalaria pfeifferi on the survival and infectivity of Schistosoma mansoni cercariae

Schistosoma mansoni cercariae from post-aestivated Biomphalaria pfeifferi remain motile for 20 hours after release. Thereafter, their activity decreases with age. The difference in mortality rate of cercariae from aestivated and non-aestivated B. pfeifferi studied here proved to be statistically significant (P<0.05) within the first 10 hours of the experimental period. Results of the percentage recovery of worms from different mouse organs infected with cercariae from aestivated and non-aestivated snails varied. The two main organs infected were the liver and intestine. In conclusion, the penetration, migration and maturation of cercariae into adult worms were not affected by the aestivation of B. pfeifferi.