Shape-Memory Polymers for Biomedical Applications

被引：114
|
作者：
Yakacki, Christopher M. [1 ,2 ]
Gall, Ken [1 ,2 ,3 ]
机构：
[1] MedShape Solut, Res & Dev, Atlanta, GA 30318 USA
[2] Georgia Inst Technol, Sch Mat Sci & Engn, Atlanta, GA 30332 USA
[3] Georgia Inst Technol, George Woodruff Sch Mech Engn, Atlanta, GA 30332 USA
来源：
SHAPE-MEMORY POLYMERS | 2010年 / 226卷
关键词：
Biocompatibility; Biomedical applications; Medical devices; Shape-memory polymers; POLYETHER-BASED POLYURETHANES; DRUG-ELUTING STENTS; OLIGO(EPSILON-CAPROLACTONE) SEGMENTS; THERMOMECHANICAL PROPERTIES; HOLDING CONDITIONS; ISCHEMIC-STROKE; MEDICAL DEVICES; BEAM RADIATION; GRAFT FIXATION; PART I;
D O I：
10.1007/12_2009_23
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Shape-memory polymers (SMPs) are a class of mechanically functional "smart" materials that have generated substantial interest for biomedical applications. SMPs offer the ability to promote minimally invasive surgery, provide structural support, exert stabilizing forces, elute therapeutic agents, and biodegrade. This review focuses on several areas of biomedicine including vascular, orthopedic, and neuronal applications with respect to the progress and potential for SMPs to improve the standard of treatment in these areas. Fundamental studies on proposed biomedical SMP systems are discussed with regards to biodegradability, tailorability, sterilization, and biocompatibility. Lastly, a proposed research and development pathway for SMP-based biomedical devices is proposed based on trends in the recent literature.
引用
收藏
页码：147 / 175
页数：29
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